Gastro-intestinal lesions are not relatable to diarrhoea or specific pathogens in post-weaning diarrhoea (PWD) in pigs

Table 5 Histopathological manifestations in the jejunum, ileum and colon and the various combinations of pathogens in pigs with and without post-weaning diarrhoea (PWD)

Histopathology Pathogen (n)	Jejunum (n)									Ileum (n)
Histopathology Pathogen (n)	Crypt abscesses (abundant/few)	Dilated crypts	Eosinophilic granulocyte infiltration	Haemorrhage	Hyperleukocytosis	Hyperplastic crypts	Hypersecretion	Necrosis	Neutrophilic granulocyte infiltration	Crypt abscesses (abundant/few)	Dilated crypts	Eosinophilic granulocyte infiltration	Haemorrhage	Hyperleukocytosis
Cases with PWD
Haemolytic E. coli (non ETEC) and rotavirus A (18*)	0/2	0	7	0	2	0	0	0	0	0/9	6	15	1	4
ETEC (> 50% haemolytic colonies) and rotavirus A (18^a)	0/3	0	5	0	4	0	0	0	3	2/4	9	14	0	6
Controls without PWD
Haemolytic E. coli (non ETEC) and rotavirus A (13)	0/1	0	6	0	0	2	0	0	0	0/7	4	9	0	0
ETEC (> 50% haemolytic colonies) and rotavirus A (8^b)	0/0	0	2	0	1	0	0	0	3	0/8	2	6	0	2

Histopathology Pathogen (n)	Ileum (n)				Colon (n)
Histopathology Pathogen (n)	Hyperplastic crypts	Hypersecretion	Necrosis	Neutrophilic granulocyte infiltration	Crypt abscesses (abundant/few)	Dilated crypts	Eosinophilic granulocyte infiltration	Haemorrhage	Hyperleukocytosis	Hyperplastic crypts	Hypersecretion	Necrosis	Neutrophilic granulocyte infiltration
Cases with PWD
Haemolytic E. coli (non ETEC) and rotavirus A (18*)	8	6	0	1	1/8	5	0	0	2	15	5	0	2
ETEC (> 50% haemolytic colonies) and rotavirus A (18^a)	11	9	2	3	5/10	8	0	0	1	17	7	0	3
Controls without PWD
Haemolytic E. coli (non ETEC) and rotavirus A (13)	6	4	0	0	0/6	4	0	1	0	10	4	1	2
ETEC (> 50% haemolytic colonies) and rotavirus A (8^b)	4	2	0	0	0/4	2	0	1	0	6	2	0	2

For each combination of pathogens, the total number of positive pigs is listed in the parenthesis in the first column. Moreover, the numbers of pigs with specific lesions within the different intestinal regions are presented for each of the pathogens
ETEC: Enterotoxigenic E. coli
n: Number of positive pigs
*Two of the pigs had missing values in one or more of the variables due to autolysis
^aOne of the pigs had missing values in one of the variables (dilated crypts in colon) due to autolysis
^bOne of the pigs had missing values in several of the variables in jejunum due to autolysis

ISSN: 1751-0147