| TIR (grade) | IZ (%) |
---|
| d10 | d27 | d10 | d27 |
---|
Horse | PLGA | PDO | PDO | PLGA | PDO | PDO |
---|
#2 | 1 | 2 | | 50 | 40 | |
#3 | 1 | 3 | 1 | 15 | 25 | 10 |
#4 | 2 | 1 | 1 | 100 | 15 | 15 |
#5 | 2 | 3 | 1 | 85 | 85 | 10 |
#6 | 2 | 2 | 1 | 60* | 20 | 10 |
#7 | 1 | 2 | 2 | 30 | 90 | 15 |
#8 | 2 | 2 | 1 | 50 | 50 | 35¤ |
Median(IQR) | 2 (1–2) | 2 (2–3) | 1 (1–1) | 50 (30–85) | 40 (20–85) | 12,5 (10–20) |
- The tissue inflammatory reaction in samples collected at day (d) 10 and 27 was assessed with histology using a modified Ehrlich-Hunt numerical scale from 0–3. The inflammatory zone was semi-quantified as a proportion of the total field view using the lowest magnification (4x objective)
- * 4% of the inflammatory reaction were represented of eosinophils
- ¤ 20% of the inflammatory reaction were represented of lymphocytes
- IQR, Inter quartile range; PDO, Polydioxanone; PLGA, Poly(lactid-co-glycolic acid)