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Fig. 2 | Acta Veterinaria Scandinavica

Fig. 2

From: Challenges in diagnosing canine spindle cell tumours using immunohistochemistry, illustrated by three nonpigmented malignant cases from the nictitating membrane

Fig. 2

Melanoma in the nictitating membrane of a 12-year-old Akita. (a) Melanoma in situ before first resection. The tumour arises from the palpebral side of the nictitating membrane of the right eye and has a firm hyperemic appearance. (b) A population of spindle cells forming irregular interlacing fascicles is present, with numerous scattered mitotic figures present in the field. Hematoxylin and eosin (bar = 200 μm). (c) Immunohistochemical stain for Melan-A showing moderate cytoplasmic staining of the neoplastic cells (bar = 200 μm). (d) Immunohistochemical stain for PNL2 showing robust cytoplasmic staining of neoplastic cells (bar = 100 μm)

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Acta Veterinaria Scandinavica

ISSN: 1751-0147