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Fig. 3 | Acta Veterinaria Scandinavica

Fig. 3

From: Challenges in diagnosing canine spindle cell tumours using immunohistochemistry, illustrated by three nonpigmented malignant cases from the nictitating membrane

Fig. 3

Melanoma in the nictitating membrane of a 14-year-old Shetland Sheepdog. (a) Melanoma in situ before second resection. The tumour arises from the palpebral surface of the membrana nictitans of the right eye and is pedunculated and ulcerated. (b) Neoplastic cells form short interlacing bundles and aggregates with sparse fibrovascular stroma admixed. Hematoxylin and eosin (bar = 200 μm). (c) Immunohistochemical stain for Melan-A is negative in this tumour (bar = 100 μm). (d) Immunohistochemical stain for PNL2 showing moderate cytoplasmic staining of neoplastic cells (bar = 200 μm)

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Acta Veterinaria Scandinavica

ISSN: 1751-0147