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Table 2 Controlled investigations on the prophylactic effect of oral calcium drenching supplementary to i.v. treatment on milk fever recurrence. Preventive effect was calculated as percentage reduction in milk fever recurrence among orally supplemented cows as compared to controls.

From: Milk Fever Control Principles: A Review

Reference Supplemental treatment Preventive effect on milk fever recurrence1) (Recurrence incidence in experimentals vs. controls, %) Comments
[80] Calcium chloride solution (aq.) × 1
126 g Ca/dose2)
70%
(7.6 vs. 25.0)
No apparent side-effects. Two different types of i.v. treatment were used.
[91] a) Calcium chloride solution (aq.) × 1
54.5 – 109.0 g Ca/dose 2)
b) Calcium chloride solution (aq.) × 1
54.5 – 109.0 g Ca/dose 2)
77%
(12.8 vs. 55.6)
65%
(9.5 vs. 27.1)
Different types of i.v. treatments in the two experiments (a and b). The amount of calcium given p.o. depended on the size of the cow.
[57] a) Calcium chloride gel × 1
72.2 g Ca/dose 2)
b) Calcium chloride gel × 1
111.9 g Ca/dose 2)
45%
(25.0 vs. 45.6)
34%
(29.9 vs. 45.6)
Within each experiment (a and b) 4 different types of i.v. treatments were used.
[20] Calcium chloride oil × 2
50 g Ca/dose
68%
(7.7 vs. 24.3)
 
  1. 1) Preventive effect = 1 - RR = 1 - (incidence rate of milk fever recurrence among experimental cows/incidence rate of milk fever recurrence among control cows).
  2. 2) The Ca dose was calculated based on information about the CaCl2 dose.