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Table 1 Results from interferon gamma immunoassays (IFN-γ), and serological, pathological and bacteriological examination of 45 animals in a dairy herd

From: Description of the Infection Status in a Norwegian Cattle Herd Naturally Infected by Mycobacterium avium subsp. paratuberculosis

Age (Years)

IFNγ1

Serology2

Pathology3

Bacteriology faeces/organs

No of animals

9

+

-

-

-/-

1

 

nd

++

Granulomatous enteritis Acid fast rods

M. a. paratuberculosis/M. a. paratuberculosis

14

 

nd

++

-

-/-

14

5

+

++

-

-/-

2

 

-

++

Granulomatous enteritis Acid fast rods

-/-

1

 

-

+/-

-

-/-

1

 

-

-

Granulomatous enteritis Acid fast rods

-/M. a. paratuberculosis

1

 

nd

-

-

-/-

1

4

++

++

Granulomatous enteritis Acid fast rods

Mycobacterium sp/-

1

 

++

++

-

-/-

1

 

++

-

-

-/-

2

 

+

-

-

-/-

1

 

-

++

-

-/-

1

 

-

-

-

-/-

2

3

-

-

-

-/-

1

 

nd

-

-

-/-

1

2.5

++

+/-

-

-/-

1

 

+

+/-

-

-/-

1

 

+

-

-

-/-

2

 

-

++

-

-/-

1

 

-

-

-

-/-

1

1.5

++

+/-

-

-/-

1

 

++

-

-

Mycobacterium sp/-

1

 

++

-

-

-/-

1

 

+

-

-

-/-

1

 

-

-

-

-/-

1

1.0

++

++

-

-/-

1

 

++

-

-

-/-

1

 

+

-

-

-/-

2

 

-

+/-

-

-/-

1

 

-

-

-

-/-

4

0.5

+

-

-

-/-

2

 

-

-

-

-/-

4

  1. 1 IFN-γgositive (++): OD ≥ 0.4; Weakly positive (+): OD ≥ 0.1 and <0.4; Negative (-): OD < 0.1.
  2. 2 ELISA Positive (++): S/P ≥ 0.3; Doubtful (+/-): S/P ≥ 0.15 and <0.3; Negative (-): S/P < 0.15.
  3. 3 Granulomatous enteritis without identification of acid-fast rods was considered a negative finding having aetiology other than infection with Mycobacterium avium subsp. paratuberculosis. Occasional small inflammatory foci without identification of acid-fast rods were seen. In over 50% of these lesions, the inflammatory cells contained pigment or foreign material such as coccidia and plant material.
  4. 4 Animals that underwent full post-mortem examination.
  5. nd = Not done
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Acta Veterinaria Scandinavica

ISSN: 1751-0147