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Table 1 Number of dogs participating in a clinical controlled therapy trial of 80 dogs with different degrees of canine hip dysplasia. The dogs were randomly assigned to receive either gold bead implantation or placebo in a blinded 6-month study. The dogs in the placebo group were thereafter offered a crossover to gold bead implantation, and all dogs were followed in an open trial for another 18 months.

From: Stratification, Blinding and Placebo Effect in a Randomized, Double Blind Placebo-controlled Clinical Trial of Gold Bead Implantation in Dogs with Hip Dysplasia

  Double blinded controlled clinical trial over six months Open clinical trial Follow up 18 months
Treatment Completed no. of dogs Drop out Withdrawal Completed no. of dogs Drop out Withdrawal
Gold 36 2 0 32 2 2
Placebo 42 0 0 7 2 0
Gold, follow up period * * * 29 1 3
Total 78 2 0 68 5 5
  1. * = not applicable