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Table 4 Distribution of 78 dogs in a blinded clinical trial of canine hip dysplasia (CHD) with gold bead implantation or placebo treatment according to the main outcome variable, change in pain signs of CHD, versus the owner's guess of treatment given. The opinion of the owner was requested at the end of the blinded trial period (six months), but before the randomization code was broken.

From: Stratification, Blinding and Placebo Effect in a Randomized, Double Blind Placebo-controlled Clinical Trial of Gold Bead Implantation in Dogs with Hip Dysplasia

  Pain signs of canine hip dysplasia  
Owner's guess of treatment given Complete recovery Large improvement Mild improvement No change in signs Mild aggravation Large aggravation Total number of dogs
Placebo 0 0 1 6 2 2 11
Gold 11 28 10 3 0 0 52
Don't know 0 0 2 10 1 2 15