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Table 6 Distribution of 68 dogs according to change in pain signs of hip dysplasia (CHD) after gold bead implantation in a controlled clinical trial of CHD. The treatment effect for gold bead implantation is given in the blinded trial versus the open treatment trial.

From: Stratification, Blinding and Placebo Effect in a Randomized, Double Blind Placebo-controlled Clinical Trial of Gold Bead Implantation in Dogs with Hip Dysplasia

  Pain signs of canine hip dysplasia  
Treatment Complete recovery Large improvement Mild improvement No change in signs Mild aggravation Large aggravation Total number of dogs
Blinded gold 5 17 8 6 0 0 36
Open gold 1 14 9 2 4 2 32