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Table 2 Tumor response to doxorubicin in vitro treatment.

From: Tumor slices as a model to evaluate doxorubicin in vitro treatment and expression of trios of genes PRSS11, MTSS1, CLPTM1 and PRSS11, MTSS1, SMYD2 in canine mammary gland cancer

Patient

Cell number in control samples

Cell number in treated samples

Cell number variation (%)

Response

1

2307

1543

- 33,12

R

2

335

297

- 11,34

NR

3

2611

2472

- 5,32

NR

4

2800

2575

- 8,04

NR

5

472

216

- 54,24

R

6

445

278

- 37,53

R

7

354

304

- 14,12

NR

8

1339

1412

+ 5,45

NR

9

1581

1337

- 15,43

NR

10

1405

625

- 55,52

R

11

644

656

+ 1,86

NR

12

699

700

+ 0,14

NR

13

5414

5086

- 6,06

NR

14

2816

2602

- 7,60

NR

15

1268

1095

- 13,64

NR

16

1851

1644

- 11,18

NR

17

11189

9691

- 13,39

NR

18

4964

3713

- 25,20

R

19

1047

1031

- 1,53

NR

20

1869

1656

- 11,40

NR

21

1629

1199

- 26,40

R

22

1675

1234

- 26,33

R

23

1879

1722

- 8,36

NR

24

2155

2103

- 2,41

NR

25

668

576

- 13,77

NR

26

4849

4262

- 12,11

NR

27

3329

3266

- 1,89

NR

28

4376

3396

- 22,39

R

29

3559

2863

- 19,56

NR

30

2716

2932

+ 7,95

NR

31

4605

3569

- 22,50

R

32

5025

4242

- 15,58

NR

33

4239

4147

- 2,17

NR

34

4334

4146

- 4,34

NR

35

3691

4131

+ 11,92

NR

36

5841

4659

- 20,24

NR

37

2201

2256

+ 2,50

NR

38

5578

4533

- 18,73

NR

  1. Cell number was counted in control (untreated) and doxorubicin treated samples. The signal (-) stands for the percentage cell reduction and (+) for the percentage cell increase, in treated as compared to control samples. R: responsive (reduction in cell number ≥ 21.7%); NR: non-responsive (reduction < 21.7%).