TY - JOUR AU - Kilpinen, Susanne AU - Spillmann, Thomas AU - Syrjä, Pernilla AU - Skrzypczak, Teresa AU - Louhelainen, Maria AU - Westermarck, Elias PY - 2011 DA - 2011/04/14 TI - Effect of tylosin on dogs with suspected tylosin-responsive diarrhea: a placebo-controlled, randomized, double-blinded, prospective clinical trial JO - Acta Veterinaria Scandinavica SP - 26 VL - 53 IS - 1 AB - The macrolid antibiotic tylosin has been widely used to treat canine chronic diarrhea, although its efficacy is based on anecdotal reports and experimental studies in dogs and not on strong scientific evidence. The term tylosin-responsive diarrhea (TRD) refers to diarrheal disorders responding to tylosin therapy within a few days. In TRD, the stool remains normal as long as tylosin treatment continues, but diarrhea reappears in many dogs within weeks after discontinuation. The aim of our trial was to assess the effect of tylosin on fecal consistency compared with a placebo treatment in dogs with suspected TRD and additionally to establish whether tylosin in dogs with recurrent diarrhea is as effective as empirical studies and anecdotal reports suggest. SN - 1751-0147 UR - https://doi.org/10.1186/1751-0147-53-26 DO - 10.1186/1751-0147-53-26 ID - Kilpinen2011 ER -