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Figure 1 | Acta Veterinaria Scandinavica

Figure 1

From: Hypertrophic cardiomyopathy in young Maine Coon cats caused by the p.A31P cMyBP-C mutation - the clinical significance of having the mutation

Figure 1

The correlation with age and diastolic IVS and LVFW measurements as a function of c.91C MYBPC3 alleles. Top: Plot of diastolic IVS correlation with age as a function numbers of c.91C MYBPC3 alleles. There was tendency to an increasing effect of p.A31P cMyBP-C homozygosity with age, though the tendency was not significant, ρ = 0.41, P = 0.09. There was only a low effect of being p.A31P cMyBP-C heterozygous, ρ = 0.09, P = 0.4. Bottom: Plot of diastolic LVFW correlation with age as a function of numbers of MYBPC3 c.91C alleles. The tendency was more weak than seen above, ρ = 0.2, P = 0.50. Red indicates the cMyBP-C wild type coordinates and the corresponding line of tendency. Green indicates p.A31P cMyBP-C heterozygous coordinates and the corresponding line of tendency. Blue indicates p.A31P cMyBP-C homozygous where and the corresponding line of tendency. Figure abbreviations: IVSd: diastolic interventricular septum, LVFWd: diastolic left ventricle free wall.

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