| |
2008
|
2009
|
|---|
| |
NW
|
ON
|
P-value
|
NW
|
ON
#
|
P-value
|
|
Incubation period (days)
|
3.0 ± 0.0
|
2.9 ± 0.3
|
ns
|
3.0 ± 0.0
|
9.6 ± 2.4
|
p < 0.0001
|
|
Max. temp. (°C)
|
41.87 ± 0.18
|
41.64 ± 0.11
|
ns
|
41.86 ± 0.13
|
40.96 ± 0.54
|
p < 0.001
|
|
Duration of fever (days)
|
8.9 ± 2.77
|
5.6 ± 1.02
|
p < 0.01
|
8.0 ± 3.07
|
5.4 ± 3.11
|
Ns
|
|
Magnitude of fever (mm
2
)
|
912 ± 158
|
503 ± 89
|
p < 0.001
|
737 ± 231
|
275 ± 174
|
p < 0.001
|
|
Nadir of neutropenia (<0.7 × 10
9
litre
-1
)
|
0.22 ± 0.06
|
0.22 ± 0.08
|
ns
|
0.26 ± 0.10
|
0.28 ± 0.15
|
Ns
|
|
Duration of neutropenia (days)
|
9.1 ± 2.38
|
10.1 ± 2.21
|
ns
|
6.7 ± 2.24
|
5.7 ± 2.49
|
Ns
|
|
Max. infection rate (%)
|
49.0 ± 3.46
|
44.6 ± 5.66
|
ns
|
52.9 ± 1.79
|
46.6 ± 9.76
|
Ns
|
|
Weight loss (%)
a
|
- 10.7 ± 3.21
|
-9.5 ± 4.63
|
ns
|
-9.6 ± 2.81
|
1.4 ± 4.20
|
p < 0.001
|
- a weight loss was measured one week after inoculation; ns - not significant
- # only seven lambs were infected
- The study was performed in two subsequent years, 2008 and 2009, respectively. Ten lambs in each group were inoculated. A two-sample t test was used for statistical analysis
