Figure 2
From: Morphological and immunohistochemical characterisation of seminomas in Norwegian dogs
Immunohistochemistry (IHC) of canine seminoma observed in the present study compared with human classical seminoma. (a) Canine seminoma (same as in Figure1 a). Scattered cells are strongly positive for PLAP (arrows). PLAP IHC. Bar, 20 μm. (b) Human classical seminoma. There is a distinct reticular pattern of PLAP-staining (arrows), indicating membranous expression. PLAP IHC. Bar, 20 μm. (c) Canine seminoma (same as in Figure1a). There is strong cytoplasmic staining for c-KIT (arrows). c-KIT IHC. Bar, 20 μm. (d) Human classical seminoma. Most cells show strong membranous and some cytoplasmic signal for c-KIT (arrows). c-KIT IHC. Bar, 20 μm.