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Table 3 Results (± standard deviation, range) of routine blood tests performed before and after 12 weeks of treatment with spot-on moxidectin/imidacloprid in 11 dogs with hyperadrenocorticism and generalized demodicosis

From: Treatment of canine generalized demodicosis associated with hyperadrenocorticism with spot-on moxidectin and imidacloprid

Parameter

Reference range

Before treatment

After 12 weeks of treatment

Hemoglobin (g/dl)

11.5–18

15.2 ± 1.0

15.2 ± 1.0

(13.8–16.7)

(13.7–16.7)

Packed cell volume (%)

35–52

42.7 ± 2.6

41.8 ± 3.0

(39–47)

(38–48)

Red blood cells (× 106/μl)

5.2–7.5

6.1 ± 0.4 (5.5–6.9)

6.0 ± 0.5

 

(5.6–7.1)

White blood cells (/μl)

6000–15,500

14,718 ± 1549

11,963 ± 1601*

(12,400–17,600)

(9700–14,200)

Albumin (g/dl)

2.6–3.7

2.9 ± 0.2

2.9 ± 0.2

(2.6–3.2)

(2.6–3.1)

Alkaline phosphatase (U/l)

27–219

268.5 ± 194.8

244.5 ± 150.0

(90–752)

(112–630)

Alanine aminotransferase (U/l)

20–123

98.6 ± 33.0 (67–170)

94.6 ± 22.2

 

(53–130)

Blood urea nitrogen (mg/dl)

7–27

24.0 ± 5.6

24.5 ± 5.4

(15–31)

(16–32)

Creatinine (mg/dl)

0.5–1.5

1.4 ± 0.2

1.3 ± 0.2

(1.1–1.6)

(1.0–1.7)

Glucose (mg/dl)

82–121

108.0 ± 8.3

108.2 ± 11.1

(97–119)

(90–121)

Globulin (g/dl)

2.8–4.8

4.2 ± 0.3

4.1 ± 0.2

(3.8–4.6)

(3.8–4.5)

  1. *P < 0.05 vs. pretreatment.