Serological markers of Bornavirus infection found in horses in Iceland

Table 1 Clinical signs and history of horses in the affected stable (stable A)

Horse ID/age	Day 0	Day 7	Day 14	Day 21
1.	Ataxia and reduced appetite	Temporary improvements	Severe ataxia/paralysis and loss of appetite	Euthanized
21 y	Treatment 1^a at day 4	Temporary improvements	Treatment 2^b	Euthanized
2.^c	No clinical signs	No clinical signs	Ataxia, depression and reduced appetite	Slow recovery
21 y	No clinical signs	No clinical signs	Treatment 2^b	Slow recovery
3.	No clinical signs	No clinical signs	Ataxia, mild excitation and reduced appetite	Slow recovery
12 y	No clinical signs	No clinical signs	Treatment 2^b	Slow recovery
4.	No clinical signs	No clinical signs	Ataxia, mild excitation and reduced appetite	Slow recovery
18 y	No clinical signs	No clinical signs	Treatment 2^b	Slow recovery
5.	No clinical signs	No clinical signs	Mild signs of ataxia and excitation	Recovery
13 y	No clinical signs	No clinical signs	Treatment 2^b	Recovery
6.	No clinical signs	No clinical signs	Mild signs of ataxia	Recovery
6 y	No clinical signs	No clinical signs	Treatment 2^b	Recovery
7.	No clinical signs	No clinical signs	No clear signs	Recovery
9 y	No clinical signs	No clinical signs	Treatment 2^b	Recovery
8.	Arrived to the stable 10 days earlier. No clinical signs	No clinical signs	No clinical signs	No clinical signs

^aTreatment 1 is dexamethasone 20 mg/day for 6 days i.m., procaine benzyl penicillin 4000 mg/day for 6 days i.m.
^bTreatment 2 is oxytetracycline 4000 mg i.v. once, glucose 30% 1000 ml i.v. once, metamizole 1500 mg i.v. once, dexamethasone 20 mg/day i.m. daily for 8 days, ampicillin 1.67 g/day i.m. daily for 6 days, with additional support: medical coal p.o. daily for 8 days, Prolac AB p.o. daily for 6 days, Pro-Bran (Protexin, Probiotics, Somerset, UK) p.o. daily for 12 days, Ferro Complex (Blue Hors, Randbøl, Denmark) p.o. for 1 month.
^cThis horse was euthanized approx. 6 months after the onset of signs, because of age and a history of intermittent lameness, most likely independent of the neurological signs.

ISSN: 1751-0147