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Table 1 Basic pharmacokinetic parameters of ivermectin administered orally (as mixture or paste), or subcutaneously to reindeer calves at 200 μg/kg, mean and standard deviation

From: The relative plasma availabilities of ivermectin in reindeer (Rangifer tarandus tarandus) following subcutaneous and two different oral formulation applications

Parameter

Group 1, mixture

Group 2, paste

Group 3, injection

Tmax (days)

2

1

2

Cmax (ng/ml)

30.2 ± 3.9a

14.9 ± 5.7b

63.1 ± 13.1c

AUC (ng*h/ml)

2881 ± 462a

1299 ± 342b

6718 ± 1620c

Frel

0.43

0.19

1

  1. Means of the groups marked with different letters (a, b, c) differ significantly (P < 0.05).