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Table 1 Baseline characteristics in the control, pituitary-dependent hyperadrenocorticism (PDH), and adrenal-dependent hyperadrenocorticism (ADH) groups

From: Assessment of left ventricular function by two-dimensional speckle-tracking echocardiography in small breed dogs with hyperadrenocorticism

Variables

Control (n  = 9)

PDH (n  = 10)

ADH (n  = 9)

Age (y/o)

10.5 ± 2.8

12.5 ± 2.0

12.3 ± 2.0

Body weight (kg)

6.2 ± 2.7

4.5 ± 1.4

5.9 ± 2.7

Female to male

0.8

1

2

Heart rate (bpm)

128.9 ± 23.4

124.6 ± 16.8

129.3 ± 13.7

Blood pressure (mmHg)

134.6 ± 11.1

140.4 ± 11.0

156.2 ± 16.5‡†

Incidence of hypertension (%)

0%

10%

56%‡†

LVEDD (mm)

24.9 ± 3.8

23.6 ± 7.0

21.0 ± 4.8

LVESD (mm)

14.1 ± 2.8

12.9 ± 3.8

12.3 ± 3.1

LVFWd (mm)

4.9 ± 1.1

6.3 ± 1.0

6.4 ± 1.0

IVSd (mm)

5.1 ± 0.8

6.6 ± 1.2

7.1 ± 1.0‡†

Incidence of LVH (%)

0%

40%

56%

LA/Ao ratio

1.4 ± 0.1

1.5 ± 0.2

1.4 ± 0.2

EF (%)

75.4 ± 9.5

79.5 ± 5.6

75.0 ± 6.1

FS (%)

43.0 ± 8.0

46.1 ± 5.3

41.3 ± 5.1

Mitral peak E wave (m/s)

0.82 ± 0.33

0.63 ± 0.13

0.52 ± 0.20

Mitral E/A ratio

1.07 ± 0.35

0.94 ± 0.29

0.75 ± 0.38

Tricuspid peak E wave (m/s)

0.50 ± 0.16

0.41 ± 0.10

0.46 ± 0.23

Tricuspid E/A ratio

0.97 ± 0.31

0.94 ± 0.23

0.86 ± 0.43

IVRT (mm)

47.9 ± 8.7

57.4 ± 13.7

64.2 ± 20.3‡†

E/IVRT

1.51 ± 0.34

0.92 ± 0.30

0.89 ± 0.42

  1. Indices are presented as mean ± SD.
  2. E/A ratio, early diastolic velocity/late diastolic velocity ratio; EF, ejection fraction; FS, fractional shortening; IVRT, isovolumetric relaxation time; IVSd, thickness of interventricular septum at end-diastole; LA/Ao, left atrial/aortic root ratio; LVEDD, left ventricular dimension at end-diastole; LVESD, left ventricular dimension at end-systole; LVFWd, thickness of left ventricular free wall at end-diastole, LVH, left ventricular hypertrophy.
  3. P < 0.05 relative to controls; P < 0.05 relative to PDH.