A KCNJ10 mutation previously identified in the Russell group of terriers also occurs in Smooth-Haired Fox Terriers with hereditary ataxia and in related breeds

Table 2 The distribution of 2052 KCNJ10:c.627C>G genotypes in 25 different dog breeds

Breed	Mut^a/Mut	Mut/Wt^a	Wt/Wt	Number tested	G allele frequency	Home country of dogs carrying the Mut allele (Mut/Mut, Mut/Wt)
Jack Russell Terrier	15	153	1071	1239	0.074	USA (13,144), Canada (0,3), France (1,0), Germany (1,6)
Parson Russell Terrier	4	51	429	484	0.061	USA (3,36), Canada (0,1), Germany (1,13), Norway (0,1)
Russell Terrier	0	12	73	85	0.071	USA (0,11), Canada (0,1)
Smooth-Haired Fox Terrier	3	0	33	36	0.083	Sweden (2,0), Norway (1,0)
Tenterfield Terrier	0	5	52	57	0.044	Australia (0,5)
Toy Fox Terrier	2	4	17	23	0.174	USA (2,4)
Other Breeds^b	0	0	128	128	0
Total	24	225	1803	2052

^aMut = mutated allele, Wt = wild type allele
^bBreed (number tested): Airedale Terrier (4), American Hairless Terrier (3), American Staffordshire Terrier (2), Australian Cattle Dog (3), Border Terrier (12), Bull Terrier (1), Danish-Swedish Farm Dog (1), Decker Terrier (1), Irish Terrier (1), Jagdterrier (31), Kerry Blue Terrier (3), Manchester Terrier (2), Miniature Bull Terrier (48), Pit Bull Terrier (3), Rat Terrier (1), Silky Terrier (1), Soft Coated Wheaten Terrier (5), Staffordshire Bull Terrier (1), Wirehaired Fox Terrier (5)

ISSN: 1751-0147