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Table 1 Summary of the epidemiological data, clinical signs and ventricle-brain ration before and after acetazolamide therapy and after surgical therapy in six dogs with idiopathic internal hydrocephalus

From: Effect of acetazolamide and subsequent ventriculo-peritoneal shunting on clinical signs and ventricular volumes in dogs with internal hydrocephalus

Breed

Gender

Age (weeks)

Neurologic signs on admission

Duration of signs (weeks)

Neurologic signs 6 weeks after acetazolamide therapy

Neurologic signs 6 weeks after surgery

Ventricle-brain ratio before treatment

Ventricle-brain ratio after acetozaolamide therapy

Ventricle-brain ratio after surgery

Chihuahua

Male intact

12

Obtundation circling, bilateral ventrolateral strabismus

~8

Obtundation circling, bilateral ventrolateral strabismus

None

0.26

0.3

0.05

Boston Terrier

Male intact

22

Obtundation, circling, aimless barking

~4

Obtundation, circling, aimless barking

None

0.5

0.48

0.5

Jack Russel Terrier

Female intact

18

Posttectal visual deficits, absent menace response

~10

Posttectal visual deficits, absent menace response

Posttectal visual deficits, absent menace response

0.3

0.35

0.08

Chihuahua

Female intact

21

Obtundation, mild ataxia on all four limbs

~12

Obtundation, mild ataxia on all four limbs

None

0.35

0.4

0.04

Mixed breed

Female intact

20

Obtundation, mild ataxia on all four limbs, hypermetric gait

~8

Obtundation, mild ataxia on all four limbs, hypermetric gait

None

0.33

0.36

0.03

Dachshund

Female intact

28

Visual deficits, reduced menace response

~12

Visual deficits, reduced menace response

None

0.36

0.4

0.08