Table 1 Morphological criteria for the assessment of ileal damage
From: A novel model for studying ileitis-induced visceral hypersensitivity in goats
Macroscopic changes | Scores | Microscopic changes | Scores | ||
|---|---|---|---|---|---|
Adhesions | None | 0 | Crypt depth | Normal | 0 |
Minimum | 1 | <50 % reduction | 1 | ||
Involving several bowel loops | 2 | >50 % reduction | 2 | ||
Mucosal hyperemia | Normal | 0 | Inflammatory cells | No infiltration | 0 |
Mild | 1 | Few scattered cells | 1 | ||
Moderate | 2 | Distributed but not dense | 2 | ||
Severe | 3 | Dense | 3 | ||
Ulcers | None | 0 | Blood vessel congestion | Normal | 0 |
Ulceration <2 cm length | 1 | Mild | 1 | ||
Two ulcers <2 cm | 2 | Moderate | 2 | ||
More sites of ulceration or one >2 cm | 3 | Severe | 3 | ||
Wall thickness | Normal | 0 | Ulceration | Normal | 0 |
50 % increase | 1 | Moderate | 1 | ||
100 % increase | 2 | Severe | 2 | ||
Maximum scores | 10 | Maximum scores | 10 | ||