Fig. 1
Serum concentrations of C-reactive protein (CRP) in Nova Scotia Duck Tolling Retriever (NSDTR) dogs with immune-mediated rheumatic disease (IMRD) and healthy controls. Serum CRP was measured with two different validated canine-specific assay (Gentian AS, Moss, Norway), values <6.8 mg/L correspond to concentrations measured with a high-sensitive assay. The horizontal dotted line represents CRP concentration 20 mg/L, the clinical decision limit for systemic inflammation. Observe the scale break on the y-axis. IMRD ANApos, NSDTRs with IMRD and a positive indirect immunofluorescence antinuclear antibody (IIF-ANA) test; IMRD ANAneg, NSDTRs with IMRD and a negative IIF-ANA test. ***Significant difference (P < 0.001) between groups