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Table 1 Clinical signs from the right eye of 10 semi-domesticated Eurasian tundra reindeer (Rangifer tarandus tarandus) after inoculation with cervid herpesvirus 2 (CvHV2; n = 5) or a combination of CvHV2 and Moraxella bovoculi (n = 5) (data from animals inoculated with M. bovoculi alone or from control animals are not shown)

From: Cervid herpesvirus 2 and not Moraxella bovoculi caused keratoconjunctivitis in experimentally inoculated semi-domesticated Eurasian tundra reindeer

Inoculum

ID

Day 0

Day 1

Day 2

Day 3

Day 4

Day 5

Day 6

Day 7

CvHV2

R4

None

 

Pus (2)a

P-oedema (1)b

Conjunctivitis

Pus (2)

P-oedema (3)

Lacrimation

P-oedema (3)

Pus (3)

P-oedema (3)

Corneal oedema

T: 40.3

Pus (3)

P-oedema (3)

Pus (3)

P-oedema (3)

Conjunctivitis

Corneal oedema

T: 39.8

R5

None

 

Pus (1)

P-oedema (1)

Pus (3)

P-oedema (2)

Pus (3)

P-oedema (3)

Pus (3)

P-oedema (3)

Corneal oedema

Corneal ulcer: 12 mm

T: 40.5

  

R10

None

 

Pus (3)

P-oedema (1)

Conjunctivitis

Pus (3)

P-oedema (2)

Pus (3)

P-oedema (3)

Pus (3)

P-oedema (3)

Conjunctivitis

Corneal oedema

T: 40.0

  

R19

None

 

Lacrimation

Pus (1)

P-oedema (1) c

     

R21

None

 

P-oedema (1)

Lacrimation

Pus (2)

P-oedema (2)

Lacrimation

Pus (2)

P-oedema (2)

Pus (2)

P-oedema (2)

Corneal oedema

Corneal ulcer: 4 mm

Pus (3)

P-oedema (3)

Corneal oedema

Corneal ulcer: 10 mm

T: 40.1

 

CvHV2 and M. bovoculi

R1

None

Pus (1)

Lacrimation

Pus (1)

P-oedema (1)

Red sclera

Lacrimation

Pus (2)

P-oedema (2)

Pus (2)

Lacrimation

P-oedema (2)

Pus (3)

P-oedema (3)

Corneal oedema

T: 40.4

Pus (3)

P-oedema (3)

P-oedema (3)

Conjunctivitis

Corneal oedema

Corneal ulcer: 3 mm

T: 39.1

R3

None

 

Lacrimation

P-oedema (1)

Pus (3)

P-oedema (3)

Pus (3)

P-oedema (3)

P-oedema (3)

Adherent pus

Blue cornea

T: 40.0

Pus (3)

Conjunctivitis

Corneal oedema

T: 39.8

 

R7

None

 

Pus (1)

Pus (2)

Lacrimation

P-oedema (2)

Pus (2)

Lacrimation

P-oedema (2)

Pus (3)

P-oedema (3)

Conjunctivitis

Corneal oedema

T: 40.3

  

R13

None

 

Pus (1)

Lacrimation

Red sclera

P-oedema (2)

Pus (3)

Lacrimation

P-oedema (2)

Pus (3)

P-oedema (3)

Conjunctivitis

Corneal oedema

T: 40.4

   

R17

None

Dry cornea

Pus (1)

Lacrimation

P-oedema (2)

Pus (3)

P-oedema (2)

T: 40.9

    
  1. Clinical signs are indicated, relative to the day of inoculation (day 0). Observations during day 1, day 3, day 4 and day 6 were conducted without handling the animals, whereas all animals were captured (physical restraint) and sampled at day 2 and day 5
  2. The time of euthanasia for each animal is indicated with italic text
  3. aPus: (1) small amounts (clots), (2) large amounts, and (3) huge amounts of pus, adherent to eyelids/skin and covering the eye
  4. bP-oedema: periorbital oedema: (1) slight swelling of conjunctiva, (2) severe oedema, and (3) extensive oedema, periorbital tissues covering the eyeball
  5. cEuthanized due to trauma