Post weaning diarrhea in pigs: risk factors and non-colistin-based control strategies

Table 1 Microbiological and clinical outcomes of monotherapy with colistin in pigs

Bacterial agents/condition	Dose per day	Duration (days)	Sample type	Reduction in E. coli (log cfu/g)^c	Performance (ADG, g/day)	References
E. coli K99/experimental PWD	300 mg/kg of diet	7	Ileum	6.55	122^b	[154]
E. coli K99/experimental PWD	300 mg/kg of diet	7	Cecum	6.63	122^b	[154]
E. coli K99/experimental PWD	300 mg/kg of diet	10	Ileum	2.3	128^a	[77]
E. coli K99/experimental PWD	300 mg/kg of diet	10	Cecum	3.2	128^a	[77]
Weaned pigs (clinically healthy)	200 mg/kg of diet	7	N/A	N/A	229^a	[155]
ETEC mixture/experimental PWD	200 mg/kg of diet	21	Ileum	1.54	292^b	[156]
			Cecum	1.65
			Colon	0.65
ETEC mixture/experimental PWD	2.5 mg/animal (Oral-Water)	21	Fecal samples	3	283^b	[78]
Weaned pigs (clinically healthy)	40 mg/kg of diet	14	Ileum	N/A	142.2^a	[81]
			Cecum
			Colon
E. coli K88/experimental PWD	4.8 mg/kg (Oral-Water)	5	Fecal samples	4	214^a	[28]
E. coli K88/experimental PWD	9.6 mg/Kg (Oral-Water)	5	Fecal samples	4	N/A	[28]
Weaned pigs (clinically healthy)	172.8 mg/kg of diet	14	Fecal samples	4.5^d	N/A	[80]

PWD post-weaning diarrhea, ADG average daily weight gain, N/A not available, ETEC enterotoxigenic Escherichia coli
^aNot statistically significant compared to the control group
^bStatistically significant compared to the control group
^cReduction compared to the control group
^dlog cfu of Enterobacteriaceae/g

ISSN: 1751-0147