Skip to main content

Table 1 Rabies vaccination protection following an intra-cranial challenge in mice

From: Efficacy of rabies vaccines in dogs and cats and protection in a mouse model against European bat lyssavirus type 2

 

Total number of mice

Survival after challenge with

FIRD-RABV

n (%)

FI-EBLV-2

n (%)

Rabies Imovax, vaccinated twice

20

20 (100)

16 (80)

P value1

 

0.000

0.002

Rabies Imovax, vaccinated once

20

ND

15 (75)

P value1

  

0.005

Virus control 50 MLD50

5

0 (0)

0 (0)

Virus control 5 MLD50

5

2 (40)

2 (40)

Virus control 0.5 MLD50

5

4 (80)

4 (80)

Rabisin, vaccinated once

20

20 (100)

16 (80)

P value1

  

0.002

Virus control 50 MLD50

5

0 (0)

0 (0)

Virus control 5 MLD50

5

2 (40)

2 (40)

Virus control 0.5 MLD50

5

3 (60)

4 (80)

  1. 1P value derived using Fisher’s exact test for the number of vaccinated and challenged mice that survived relative to the total and compared with the 50 MLD50 virus control mice