Fig. 2From: Fatal haemorrhage and neoplastic thrombosis in a captive African lion (Panthera leo) with metastatic testicular sex cord–stromal tumourMicroscopic images, neoplasm seen at the left testicle is poorly differentiated and pleomorphic composed of a round to polygonal cells with eosinophilic cytoplasm and scattered spindle cells (arrows), HE and b signet ring cells (arrows), HE. c Marked anisocytosis, anisokaryosis and karyomegaly (arrows) was noted in the neoplastic cells, HE. d Histological section of the neoplastic thrombus at a renal vein, the attachment is composed of fibrin (arrow). The lumen is occluded by a meshwork of tumour cells with fibrin (asterisk), HE. e Tumour cells shown strong cytoplasmic positive immunolabeling for vimentin. f Cytoplasm of neoplastic cells was positive for S100Back to article page