Comparative review of human and canine osteosarcoma: morphology, epidemiology, prognosis, treatment and genetics

Table 1 Histologic subtypes of human and canine osteosarcoma

Species	Canine^a	Human^b
Subtypes	A. Central	Osteosarcoma
	Osteosarcoma	Low-grade central osteosarcoma
	a. Poorly differentiated	Conventional
	b. Osteoblastic	Chondroblastic
	Nonproductive	Fibroblastic
	Productive	Osteoblastic
	c. Chondroblastic	Secondary
	d. Fibroblastic	Telangiectatic
	e. Telangiectatic	Small cell
	f. Giant cell type	Parosteal
	B. Peripheral	Periosteal
	1. Periosteal osteosarcoma	High grade surface
	2. Parosteal osteosarcoma

^aBased on World Health Organization (WHO) International Histological Classification of Tumors of Domestic Animals [23]
^bBased on WHO Classification of Tumours of Bone [22]

ISSN: 1751-0147