Table 1 Dogs with gastric muscularis unorganized hyperechoic striations and their respective clinical and histopathological findings

Dog 1

5 years FS Welsh Corgi

No

Immune-mediated thrombocytopenia

Light patchy (microscopic) mucosal and submucosal hemorrhage; no hemorrhage in muscularis layer

Dog 2

7 years FS Bulldog

Vomiting, hematemesis

Probable immune-mediated thrombocytopenia, DIC, septicemia

Diffuse light submucosal hemorrhage; patchy muscularis hemorrhage (light) and mainly along plexus and extending perivascular into inner and outer layers

Dog 3

15 years MN Yorkshire Terrier

Inappetance, melena

Transitional cell carcinoma, cholangio-hepatitis

Mucosal layer has accentuated deep follicles, but more diffuse lymphoplasmocytic superficial lamina proprial infiltration; parietal cells with swollen hypochromatic nucleus and cytoplasmic pseudoinclusion; cut perpendicular so looks different, but impression is increased mature fibrous tissue through tunica muscularis and serosa

Dog 4

8.5 years MN mixed breed dog

No

Glomerulopathy, cerebral infarcts

Normal mucosal layer; submucosal small arteries, arterioles, and veins have pale amphophilic homogeneous mural deposition (vasculopathy); surrounding fibrous tissue has pale basophilic coarse globular/stippling; inner layer muscularis has areas with drop-out of myofibers

Dog 5

8 years MN Chow Chow

Vomiting (medication related)

Hepatocellular necrosis with liver dysfunction, portal vein thrombosis

Normal mucosa/submucosa layers; increased fibrous tissue in muscularis; perivascular fatty infiltration in muscularis

Dog 6

15 years MN Beagle

Vomiting, diarrhea, anorexia

Acute kidney injury, primary hyperparathyroidism, and multiple neoplastic disease processes (transitional cell carcinoma, hepatocellular adenoma, mantle cell lymphoma, thyroid mass). Ruptured hepatic adenoma with hemoabdomen

No abnormal histopathologic findings

Dog 7

10.5 years FS Australian Shepherd

Weight loss

Spinal meningioma, chronic kidney disease and eosinophilic enteritis

No abnormal histopathologic findings

Dog 8

9 years MN Yorkshire Terrier

Weight loss

Renal tubular dysfunction, membranoproliferative glomerulonephritis with interstitial nephritis

Small portion of the outer layer of tunica muscularis has atrophied bundles); myenteric plexus and ganglia present; space between inner and outer layers expanded by edematous fibrous tissue with dilated lymphatics; submucosa and mucosa layer with mineralization of vessels and basement membrane; fibrin thrombi in mucosal venules (azotemia)

Dog 9

10 years FS Labrador Retriever

Vomiting

Hepatocellular adenoma, pulmonary and renal amyloidosis

No tissue