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Table 1 Mucosal pro- and active MMP-2 and -9 activities in dogs with CE and healthy dogs

From: Identification of matrix metalloproteinase-2 and -9 activities within the intestinal mucosa of dogs with chronic enteropathies

Intestinal part

Group

Activity

Pro MMP-2 (AU) median (range)

Active MMP-2 (AU) median (range)

Pro MMP-9 (AU) median (range)

Active MMP-9 (AU) median (range)

Duodenum

Dogs with CE (n = 35)

0.01 (0–1.66)

0 (0–0.02)

0.06 (0–3.86)

0 (0–0.21)

Healthy dogs (n = 18)

0 (0–0.64)

0 (0–0)

0.03 (0–3.32)

0 (0–0)

Ileum

Dogs with CE (n = 12)

0.02 (0–0.83)

0 (0–0.01)

0.06 (0–0.5)

0 (0–0.28)

Healthy dogs (n = 18)

0 (0–0.52)

0 (0–0)

0.03 (0–0.45)

0 (0–0)

Colon

Dogs with CE (n = 15)

0.03 (0–0.55)

0 (0–0.05)

0.07 (0.02–0.92)

0 (0–0.04)

Healthy dogs (n = 18)

0 (0–0.64)

0 (0–0)

0 (0–0.79)

0 (0–0)

Cecum

Dogs with CE (n = 6)

0.0 (0.01–1.48)

0 (0–0.01)

0.09 (0.02–0.59)

0.005 (0–0.05)

Healthy dogs (n = 6)

0 (0–0.3)

0 (0–0)

0.18 (0–0.82)

0 (0–0)

  1. Pro- and active MMP-2 and -9 activities were measured in the mucosal samples from duodenum, ileum, colon, and cecum of dogs with CE and healthy dogs
  2. AU arbitrary units; CE chronic enteropathies; Pro pro-enzyme