Table 3 Diagnostic accuracy of blood sucrose for diagnosis of EGUS using traditional and Bayesian latent class analyses in 45 foals evaluated pre and post weaning
Lesion type | Test | Parameter | Gold standarda | Bayesian LCb |
|---|---|---|---|---|
Estimate % (95% CI) | Estimate % (95% PI) | |||
GL | Sucrose 45 | Sensitivity | 89 (78, 95) | 89 (77, 97) |
Specificity | 65 (47, 79) | 83 (65, 95) | ||
Sucrose 90 | Sensitivity | 84 (72, 92) | 81 (69, 91) | |
Specificity | 71 (53, 84) | 95 (80, 100) | ||
Endoscopy | Sensitivity | NA | 81 (70, 90) | |
Specificity | NA | 99 (95, 100) | ||
GDL | Sucrose 45 | Sensitivity | 95 (79, 99) | 97 (90, 100) |
Specificity | 47 (34, 60) | 87 (69, 98) | ||
Sucrose 90 | Sensitivity | 90 (73, 97) | 91 (80, 99) | |
Specificity | 55 (42, 67) | 97 (83, 100) | ||
Endoscopy | Sensitivity | NA | 47 (36, 59) | |
Specificity | NA | 99 (95, 100) | ||
SQL | Sucrose 45 | Sensitivity | 89 (77, 96) | 90 (78, 98) |
Specificity | 55 (39, 70) | 77 (55, 91) | ||
Sucrose 90 | Sensitivity | 87 (74, 94) | 84 (72, 94) | |
Specificity | 64 (48, 78) | 94 (76, 100) | ||
Endoscopy | Sensitivity | NA | 75 (62, 87) | |
Specificity | NA | 99 (94, 100) | ||
CSL | Sucrose 45 | Sensitivity | 94 (80, 98) | 95 (88, 99) |
Specificity | 52 (38, 66) | 89 (71, 99) | ||
Sucrose 90 | Sensitivity | 90 (75, 96) | 89 (79, 97) | |
Specificity | 58 (44, 71) | 98 (85, 100) | ||
Endoscopy | Sensitivity | NA | 60 (48, 71) | |
Specificity | NA | 99 (96, 100) |