Table 4 Median (range) sLT release (pg/mL) after incubation of peripheral blood leukocytes (PBL) with C. nubeculosus extract (Cul2: 2 μg/mL) or S. vittatum extract (Sim10: 10 μg/mL) from horses that remained healthy (H) or developed insect bite hypersensitivity (IBH) at different time points (see Table 2 for number of horses included at each time point)
From: A prospective study on insect bite hypersensitivity in horses exported from Iceland into Switzerland
Time point | Incubation of PBL with | Median (range) of sLT released (pg/mL) from horses with clinical endpoint | H versus IBH P | |
|---|---|---|---|---|
H | IBH | (MWU-testa) | ||
Iceland | Cul2 | 51 (0–109) | 56 (0–109) | Ns |
Sim10 | 17 (0–91) | 5 (0–275) | Ns | |
T − 1 | Cul2 | 51 (0–1291) | 65 (0–2763) | Ns |
Sim10 | 26 (0–2251) | 30 (0–2411) | Ns | |
T − 2 | Cul2 | 70 (0–3467) | 100 (0–5900) | < 0.01 |
Sim10 | 28 (0–4791) | 85 (0–5350) | < 0.1 | |
T − 3 | Cul2 | 60 (0–4855) | 968 (0–4827) | < 0.001 |
Sim10 | 100 (0–4745) | 718 (0–11834) | < 0.01 | |
T − 4 | Cul2 | 53 (0–4804) | 244 (3–4798) | < 0.0001 |
Sim10 | 53 (0–2402) | 323 (0–4798) | < 0.01 | |