Clinical effects of constant rate infusions of medetomidine–propofol combined with sevoflurane anesthesia in Thoroughbred racehorses undergoing arthroscopic surgery

Table 1 Cardiovascular parameters during maintenance of anesthesia

Variable	Group	Time after connection to breathing circuit (min)
Variable	Group	0	15	30	45	60
HR (beats/min)	M	–	26 ± 2	25 ± 4	26 ± 2	27 ± 1
	MP3	–	28 ± 3	29 ± 2	29 ± 2	30 ± 2
	MP6	–	28 ± 4	29 ± 4	29 ± 4	29 ± 3
SAP (mmHg)	M	–	102 ± 11	95 ± 10	104 ± 10	108 ± 6
	MP3	–	104 ± 8	103 ± 9	105 ± 8	108 ± 6
	MP6	–	111 ± 15	106 ± 10	109 ± 8	113 ± 8
DAP (mmHg)	M	–	65 ± 10	55 ± 12	60 ± 6	64 ± 5
	MP3	–	63 ± 5	62 ± 4	63 ± 5	68 ± 4
	MP6	–	67 ± 12	68 ± 7	71 ± 6	74 ± 7
MAP (mmHg)	M	–	78 ± 10	71 ± 9	75 ± 5	77 ± 3
	MP3	–	78 ± 5	77 ± 3	78 ± 4	81 ± 6
	MP6	–	82 ± 13	82 ± 8	85 ± 6	87 ± 7

Data are presented as mean ± SD
Horses were maintained with sevoflurane and CRI of either medetomidine (3.0 μg/kg/h) (Group M; n = 10); or medetomidine (3.0 μg/kg/h) and propofol (3.0 mg/kg/h) (Group MP3; n = 10); or medetomidine (3.0 μg/kg/h) and propofol (6.0 mg/kg/h) (Group MP6; n = 10)
None of the data across rows differed significantly from each other
HR heart rate, SAP systolic arterial blood pressure, DAP diastolic arterial blood pressure, MAP mean arterial blood pressure

ISSN: 1751-0147