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Table 2 Pre- and postoperative serum c-CRP concentration, number of dogs, surgical procedures and postsurgical events in Group 1, 2 and 3

From: Changes in canine C-reactive protein levels following orthopaedic surgery: a prospective study

 

Day 0

Day 1

Day 4

Day 7

Day 10

Day 13

Group 1

 Type

Peak c-CRP concentration on Day 1 and then continued to decrease

 Mean ± SD

0.83 ± 1.03b,c,e

8.10 ± 3.15a,c,e,g,i

3.76 ± 1.94a,b,e,g,i

1.63 ± 0.92a,b,c,g,i

0.96 ± 0.70b,c,e

0.68 ± 0.51b,c,e

 n

63

63

63

63

63

45

 Surgical procedures

Corrective osteotomy (n = 24), reduction of dislocation (n = 13), internal fracture fixation (n = 11), non-union repair (n = 6), ostectomy (n = 5), arthrodesis (n = 3), joint replacement (n = 1)

 Event

Non

Group 2

 Type

Peak c-CRP concentration on Day 1and Day 4, and then continued to decrease

 Mean ± SD

0.84 ± 1.10b,c,e

5.88 ± 2.27a,e,g,i,x

5.99 ± 2.21a,e,g,i,y

2.18 ± 1.08a,b,c,i

1.09 ± 0.96b,c

0.77 ± 0.55b,c,e

 n

15

15

15

15

15

11

 Surgical procedures

Corrective osteotomy (n = 9), reduction of dislocation (n = 2), non-union repair (n = 1), ostectomy (n = 1), arthrodesis (n = 2)

 Event

Swelling and/or heat at the surgical site (n = 9), visceral disease (n = 3), no identifiable causes (n = 3)

Group 3

 Type

Peak c-CRP concentration on Day 4 and then continued to decrease

 Mean ± SD

0.49 ± 0.39b,c,e,g

6.56 ± 3.69a,g,i

9.68 ± 5.67a,f,g,i,y

3.76 ± 1.75a,d,h,i,y,z

1.67 ± 0.85a,b,c,f

1.43 ± 0.96b,c,e

 n

14

14

14

14

14

11

 Surgical procedures

Corrective osteotomy (n = 7), reduction of dislocation (n = 2), non-union repair (n = 1), ostectomy (n = 2), arthrodesis (n = 2)

 Event

Swelling and/or heat sensation at the surgical site (n = 5), visceral disease (n = 4), surgical site problems (n = 2), non-surgical site problems (n = 2), no identifiable causes (n = 2)

  1. The reported values are the mean ± standard deviation (SD). c-CRP values are in mg/dL
  2. c-CRP canine C-reactive protein
  3. aGames–Howell test; P < 0.01 indicates a significant difference vs. Day 0
  4. bGames–Howell test; P < 0.01 indicates a significant difference vs. Day 1
  5. cGames–Howell test; P < 0.01 indicates a significant difference vs. Day 4
  6. dGames–Howell test; P < 0.05 indicates a significant difference vs. Day 4
  7. eGames–Howell test; P < 0.01 indicates a significant difference vs. Day 7
  8. fGames–Howell test; P < 0.05 indicates a significant difference vs. Day 7
  9. gGames–Howell test; P < 0.01 indicates a significant difference vs. Day 10
  10. hGames–Howell test; P < 0.05 indicates a significant difference vs. Day 10
  11. iGames–Howell test; P < 0.01 indicates a significant difference vs. Day 13
  12. xTukey’s honestly significant difference test; P < 0.05 indicates a significant difference vs. Group 1
  13. yGames–Howell test; P < 0.01 indicates a significant difference vs. Group 1
  14. zGames–Howell test; P < 0.05 indicates a significant difference vs. Group 2