Table 2 Effects of administering urocortins (Ucns) and their relative receptors, CRHRs, on the hypothalamic–pituitary–adrenal axis of domestic animals
Animal species | Treatment | Ucn1 | Ucn2 | Ucn3 | CRHR1 | CRHR2 | Effects | References |
|---|---|---|---|---|---|---|---|---|
Bird | ICV | n.d. | n.d. | + | n.d. | n.d. | ↑ Ghrelin | [154] |
Ewe | ICV | + | n.d. | n.d. | n.d. | n.d. | ↓ Food intake ↑ GH, LH, cortisol, leptin | [84] |
Gilt | ICV | + | n.d. | n.d. | n.d. | n.d. | ↓ LH and food intake ↑ Cortisol and ACTH | [85] |
Horse (pony) | ICV | + | n.d. | n.d. | n.d. | n.d. | ↑ Cortisol ↓ Food intake | [155] |
Pig | Central injection | + | n.d. | n.d. | + | n.d. | ↑ Cortisol | |
Sheep | ICV | + | n.d. | n.d. | n.d. | n.d. | ↑ Urine excretion ↓ Food intake | [157] |