TY - JOUR AU - Bush, K. AU - Courvalin, P. AU - Dantas, G. AU - Davies, J. AU - Eisenstein, B. AU - Huovinen, P. PY - 2011 DA - 2011// TI - Tackling antibiotic resistance JO - Nat Rev Microbiol VL - 9 UR - https://doi.org/10.1038/nrmicro2693 DO - 10.1038/nrmicro2693 ID - Bush2011 ER - TY - STD TI - European Commission. A European one health action plan against antimicrobial resistance (AMR). 2017. ID - ref2 ER - TY - STD TI - Tickell S. The antibiotic innovation study: expert voices on a critical need. 2005. http://soapimg.icecube.snowfall.se/strama/AIS%20Report%20React.pdf. UR - http://soapimg.icecube.snowfall.se/strama/AIS%20Report%20React.pdf ID - ref3 ER - TY - JOUR AU - Mouton, J. W. AU - Ambrose, P. G. AU - Canton, R. AU - Drusano, G. L. AU - Harbarth, S. AU - MacGowan, A. PY - 2011 DA - 2011// TI - Conserving antibiotics for the future: new ways to use old and new drugs from a pharmacokinetic and pharmacodynamic perspective JO - Drug Resist Updat. VL - 14 UR - https://doi.org/10.1016/j.drup.2011.02.005 DO - 10.1016/j.drup.2011.02.005 ID - Mouton2011 ER - TY - JOUR AU - MacGowan, A. PY - 2011 DA - 2011// TI - Revisiting Beta-lactams-PK/PD improves dosing of old antibiotics JO - Curr Opin Pharmacol VL - 11 UR - https://doi.org/10.1016/j.coph.2011.07.006 DO - 10.1016/j.coph.2011.07.006 ID - MacGowan2011 ER - TY - JOUR AU - Kaplan, B. AU - Kahn, L. H. AU - Monath, T. P. PY - 2009 DA - 2009// TI - The brewing storm JO - Vet Ital. VL - 45 ID - Kaplan2009 ER - TY - STD TI - The Swedish Veterinary Association. SVS: Guidelines for the use of antibiotics in production animals-cattle, pigs, sheep and goats. 2017. https://www.svf.se/media/vd5ney4l/svfs-riktlinje-antibiotika-till-produktionsdjur-eng-2017.pdf. UR - https://www.svf.se/media/vd5ney4l/svfs-riktlinje-antibiotika-till-produktionsdjur-eng-2017.pdf ID - ref7 ER - TY - JOUR AU - Sjölund, M. AU - Backhans, A. AU - Greko, C. AU - Emanuelson, U. AU - Lindberg, A. PY - 2015 DA - 2015// TI - Antimicrobial usage in 60 Swedish farrow-to-finish pig herds JO - Prev Vet Med VL - 121 UR - https://doi.org/10.1016/j.prevetmed.2015.07.005 DO - 10.1016/j.prevetmed.2015.07.005 ID - Sjölund2015 ER - TY - STD TI - Swedres-Svarm 2019. Sales of antibiotics and occurrence of resistance in Sweden. Solna/Uppsala; 2020. ID - ref9 ER - TY - STD TI - European Medicines Agency. Sales of veterinary antimicrobial agents in 31 European countries in 2017. Trends from 2010 to 2017. 9th ESVAC report. 2019. ID - ref10 ER - TY - BOOK AU - Apley, M. D. AU - Thacker, B. PY - 2003 DA - 2003// TI - Determination of the pharmacokinetics of procaine penicillin in swine administered by intra-muscular injection and with a needleless injection device, USA PB - National Pork Board CY - Des Moines, Iowa ID - Apley2003 ER - TY - STD TI - Prescott J. Beta-lactam antibiotics: penam penicillins Oxford, Blackwell Publishing Ltd. 121–37. In Antibiotic Therapy in Veterinary medicine. 5th edition. Edited by Giguère S, Prescott JF, Dowling PM. Wiley Blackwell 2013;pp. 135–52. ID - ref12 ER - TY - JOUR AU - Ranheim, B. AU - Ween, H. AU - Egeli, A. K. AU - Hormazabal, V. AU - Yndestad, M. AU - Soli, N. E. PY - 2002 DA - 2002// TI - Benzathine penicillin G and procaine penicillin G in piglets: comparison of intramuscular and subcutaneous injection JO - Vet Res Commun VL - 26 UR - https://doi.org/10.1023/A:1020590408947 DO - 10.1023/A:1020590408947 ID - Ranheim2002 ER - TY - STD TI - Summary of Product Characteristics for Ultrapen vet. https://docetp.mpa.se/LMF/Ultrapen%20vet%20300%20mg%20per%20ml%20suspension%20for%20injection%20SmPC_09001bee807a6bf9.pdf. UR - https://docetp.mpa.se/LMF/Ultrapen%20vet%20300%20mg%20per%20ml%20suspension%20for%20injection%20SmPC_09001bee807a6bf9.pdf ID - ref14 ER - TY - JOUR AU - Drusano, G. L. PY - 2004 DA - 2004// TI - Antimicrobial pharmacodynamics: critical interactions of ‘bug and drug’ JO - Nat Rev Microbiol VL - 2 UR - https://doi.org/10.1038/nrmicro862 DO - 10.1038/nrmicro862 ID - Drusano2004 ER - TY - JOUR AU - Matter, D. AU - Rossano, A. AU - Limat, S. AU - Vorlet-Fawer, L. AU - Brodard, I. AU - Perreten, V. PY - 2007 DA - 2007// TI - Antimicrobial resistance profile of Actinobacillus pleuropneumoniae and Actinobacillus porcitonsillarum JO - Vet Microbiol VL - 122 UR - https://doi.org/10.1016/j.vetmic.2007.01.009 DO - 10.1016/j.vetmic.2007.01.009 ID - Matter2007 ER - TY - JOUR AU - Keen, P. M. PY - 1965 DA - 1965// TI - The binding of three penicillins in the plasma of several mammalian species as studied by ultrafiltration at body temperature JO - Br J Pharmacol Chemother VL - 25 UR - https://doi.org/10.1111/j.1476-5381.1965.tb02068.x DO - 10.1111/j.1476-5381.1965.tb02068.x ID - Keen1965 ER - TY - STD TI - Summary of Product Characteristics for Ethacilin vet. https://docetp.mpa.se/LMF/Ethacilin%20vet.%20suspension%20for%20injection%20SmPC_09001bee807a286b.pdf: Swedish Medical Products Agency; 2019. UR - https://docetp.mpa.se/LMF/Ethacilin%20vet.%20suspension%20for%20injection%20SmPC_09001bee807a286b.pdf ID - ref18 ER - TY - JOUR AU - Wallgren, P. AU - Vallgårda, J. PY - 1993 DA - 1993// TI - Serogrisproduktion - presentation, definition och kravlista (SPF pigs–presentation, definition and list of demands) JO - Sv Vet T (Swedish Veterinary J) VL - 45 ID - Wallgren1993 ER - TY - JOUR AU - Österberg, J. AU - Wallgren, P. PY - 2008 DA - 2008// TI - Effects of a challenge dose of Salmonella Typhimurium or Salmonella Yoruba on the patterns of excretion and antibody responses of pigs JO - Vet Rec VL - 162 UR - https://doi.org/10.1136/vr.162.18.580 DO - 10.1136/vr.162.18.580 ID - Österberg2008 ER - TY - JOUR AU - Antonia, K. AU - Anastasia, A. AU - Tesseromatis, C. PY - 2012 DA - 2012// TI - Stress can affect drug pharmacokinetics via serum/tissues protein binding and blood flow rate alterations JO - Eur J Drug Metab Pharmacokinet VL - 37 UR - https://doi.org/10.1007/s13318-011-0077-2 DO - 10.1007/s13318-011-0077-2 ID - Antonia2012 ER - TY - JOUR AU - Frimodt-Moller, N. AU - Bentzon, M. W. AU - Thomsen, V. F. PY - 1986 DA - 1986// TI - Experimental infection with Streptococcus pneumoniae in mice: correlation of in vitro activity and pharmacokinetic parameters with in vivo effect for 14 cephalosporins JO - J Infect Dis VL - 154 UR - https://doi.org/10.1093/infdis/154.3.511 DO - 10.1093/infdis/154.3.511 ID - Frimodt-Moller1986 ER - TY - JOUR AU - Abdul-Aziz, M. H. AU - Lipman, J. AU - Mouton, J. W. AU - Hope, W. W. AU - Roberts, J. A. PY - 2015 DA - 2015// TI - Applying pharmacokinetic/pharmacodynamic principles in critically ill patients: optimizing efficacy and reducing resistance development JO - Semin Respir Crit Care Med VL - 36 UR - https://doi.org/10.1055/s-0034-1398490 DO - 10.1055/s-0034-1398490 ID - Abdul-Aziz2015 ER - TY - JOUR AU - Craig, W. A. PY - 1998 DA - 1998// TI - Pharmacokinetic/pharmacodynamic parameters: rationale for antibacterial dosing of mice and men JO - Clin Infect Dis VL - 26 UR - https://doi.org/10.1086/516284 DO - 10.1086/516284 ID - Craig1998 ER - TY - JOUR AU - Teran, M. T. AU - Sierra, M. AU - Garcia, J. J. AU - Diez, M. J. AU - Arin, M. J. AU - Diez, M. T. PY - 1988 DA - 1988// TI - Plasma protein binding of an N-pyrrolyl derivative penicillin in several mammalian species JO - Res Vet Sci VL - 45 UR - https://doi.org/10.1016/S0034-5288(18)30910-X DO - 10.1016/S0034-5288(18)30910-X ID - Teran1988 ER - TY - JOUR AU - Sjölund, M. AU - Fuente, A. J. AU - Fossum, C. AU - Wallgren, P. PY - 2009 DA - 2009// TI - Responses of pigs to a re-challenge with Actinobacillus pleuropneumoniae after being treated with different antimicrobials following their initial exposure JO - Vet Rec VL - 164 UR - https://doi.org/10.1136/vr.164.18.550 DO - 10.1136/vr.164.18.550 ID - Sjölund2009 ER - TY - JOUR AU - Sjölund, M. AU - Fossum, C. AU - Fuente, M. A. J. AU - Alava, M. AU - Juul-Madsen, H. R. AU - Lampreave, F. PY - 2011 DA - 2011// TI - Effects of different antimicrobial treatments on serum acute phase responses and leucocyte counts in pigs after a primary and a secondary challenge infection with Actinobacillus pleuropneumoniae JO - Vet Rec VL - 169 UR - https://doi.org/10.1136/vr.d2268 DO - 10.1136/vr.d2268 ID - Sjölund2011 ER - TY - JOUR AU - Wallgren, P. AU - Segall, T. AU - Morner, P. A. AU - Gunnarsson, A. PY - 1999 DA - 1999// TI - Experimental infections with Actinobacillus pleuropneumoniae in pigs-I. Comparison of five different parenteral antibiotic treatments JO - Zentralbl Veterinarmed B VL - 46 ID - Wallgren1999 ER -