Table 2 Results from the linear mixed model analysis on effect of treatment on SpO2, PE′CO2, fR and VT in pigs anaesthetised with either propofol 8 mg/kg/h or alfaxalone 5 mg/kg/h in combination with ketamine 5 mg/kg/h and dexmedetomidine 4 µg/kg/h (n = 16)
Variable and level | Estimate (SE) | P-value | 95% Confidence interval |
|---|---|---|---|
SpO2 | |||
Treatment | |||
Propofol | Baseline | – | – |
Alfaxalone | 3.6 (2.3) | 0.12 | − 0.87, 8.04 |
Sex | |||
Male | Baseline | – | – |
Female | 3.4 (2.3) | 0.14 | − 1.13, 8.02 |
Body weight | − 0.6 (0.3) | 0.04 | − 1.20, − 0.05 |
PE′CO2 | |||
Treatment | |||
Propofol | Baseline | – | – |
Alfaxalone | − 0.8 (0.4) | 0.05 | − 1.62, 0.01 |
Sex | |||
Male | Baseline | – | – |
Female | − 0.6 (0.4) | 0.17 | − 1.43, 0.25 |
Body weight | 0.1 (0.05) | 0.14 | − 0.03, 0.19 |
fR | |||
Treatment | |||
Propofol | Baseline | – | – |
Alfaxalone | 7.5 (3.1) | 0.01 | 1.51, 13.51 |
Sex | |||
Male | Baseline | – | – |
Female | 2.3 (3.1) | 0.47 | − 3.91, 8.41 |
Body weight | − 1.0 (0.4) | 0.02 | − 1.74, − 0.18 |
VT/kg | |||
Treatment | |||
Propofol | Baseline | – | – |
Alfaxalone | 0.0 (0.5) | 0.94 | − 1.0, 1.0 |
Sex | |||
Male | Baseline | – | – |
Female | 0.1 (0.5) | 0.80 | − 0.9, 1.2 |
Body weight | − 0.1 (0.1) | 0.235 | − 0.2, 0.1 |