Fig. 3
From: Severe deforming dermatitis in a kitten caused by Caryospora bigenetica
Histopathology of the skin in cutaneous Caryospora bigenetica infection. a A punch biopsy showing a highly cellular, transdermal, severe diffuse interstitial inflammatory infiltrate effacing the architecture, scale bar = 1 mm. b Different developmental stages of C. bigenetica are numerous throughout the dermis in macrophages and present within the keratinocytes of hair follicles, scale bar = 50 µm. c A detail of the dermal histiocytic inflammatory infiltrates effacing the dermal architecture. Protozoal parasites are present and reproducing within all macrophages, scale bar = 20 µm. d Periodic Acid Schiff (PAS) stain highlights Caryospora organisms, except for the zoites (arrows). The most abundant stage is an unsporulated oocyst presented as a capsulated aggregate of intensively staining material, scale bar = 20 µm