Fig. 1
From: Early immunohistochemical detection of pulmonary micrometastases in dogs with osteosarcoma
a Section of lung tissue from a dog with osteosarcoma with macroscopic metastases (case 2) showing a macroscopic metastasis (25 × magnification). Section of lung tissue from a dog with osteosarcoma without macroscopic metastases (case 5) showing b a microscopic metastasis lodged within a pulmonary arteriole (100 × magnification), and c a presumed micrometastasis within the alveolar septa (200 × magnification). Formalin-fixed paraffin-embedded tissue, haematoxylin & eosin stain