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Table 1 Variables (mean ± standard error of the mean (SEM)) of the physiological parameters observed during the surgical procedure in the different groups

From: Antinociceptive and analgesic effect of continuous intravenous infusion of maropitant, lidocaine and ketamine alone or in combination in cats undergoing ovariohysterectomy

Variables

Groups

Moments

M1

M2

M3

M4

M5

M6

M7

HR (bpm)

CG

150 ± 20

160 ± 23

202 ± 24

195 ± 23

183 ± 22

171 ± 24

169 ± 20

 

MG

162 ± 22

155 ± 20

181 ± 20#

188 ± 12#

177 ± 19

172 ± 21

180 ± 17#

 

LG

146 ± 23

157 ± 25

176 ± 28

178 ± 30

167 ± 25

165 ± 28

164 ± 27

 

KG

161 ± 24

148 ± 17

173 ± 16

177 ± 16

171 ± 18

169 ± 20

165 ± 20

 

LMG

136 ± 9

127 ± 7*

161 ± 17*

170 ± 20

158 ± 17

151 ± 13

133 ± 16*#

 

KMG

139 ± 15

138 ± 21

159 ± 26*#

164 ± 18*#

156 ± 21*

149 ± 17

133 ± 13*

 

LKMG

155 ± 23

153 ± 25

174 ± 16*

178 ± 18

174 ± 12

165 ± 17

154 ± 11

SBP (mmHg)

CG

72.2 ± 14.7

93.8 ± 31.6

127.2 ± 47.5

133.5 ± 39.7

113.0 ± 32.1

107.1 ± 31.9

108.5 ± 17.8

 

MG

81.5 ± 8.7

96.1 ± 36.7

114.6 ± 25.0

109 ± 19.1

97.1 ± 28.1

91.6 ± 14.9

94.1 ± 17.2

 

LG

55.0 ± 11.9

71.2 ± 13.0

96.5 ± 32.7

92.5 ± 37.0

71.0 ± 19.4

81.75 ± 16.1

80.7 ± 16.2

 

KG

71.7 ± 15.6

90.0 ± 32.2

110.7 ± 32.4

108.5 ± 33.4

96.2 ± 42.5

95.7 ± 25.6

104.2 ± 32.6

 

LMG

67.0 ± 12.7

87.0 ± 27.5

113.7 ± 52.4

119.2 ± 54.1

101.2 ± 46.3

96.0 ± 41.5

87.5 ± 40.4

 

KMG

66.8 ± 16.9

83.3 ± 34.9

109.1 ± 53.4

105.3 ± 43.0

94.8 ± 52.9

91.1 ± 47.4

96.0 ± 46.7

 

LKMG

66.0 ± 7.0

85.0 ± 22.7

99.5 ± 19.9

101.0 ± 28.9

90.0 ± 26.4

93.2 ± 24.1

90.7 ± 20.2

RR (mpm)

CG

25 ± 6

27 ± 10

29 ± 10

31 ± 10

29 ± 11

26 ± 10

25 ± 7

 

MG

39 ± 10#

30 ± 9#

32 ± 11#

33 ± 10#

28 ± 12#

29 ± 11#

27 ± 13#

 

LG

30 ± 4•

31 ± 5•

30 ± 5•

28 ± 8

26 ± 8

25 ± 8

27 ± 7

 

KG

18 ± 9#•

18 ± 7#•

19 ± 8#•

18 ± 8A

18 ± 9

17 ± 8

20 ± 10

 

LMG

24 ± 8

16 ± 5

20 ± 7

18 ± 7A

18 ± 8

16 ± 7

16 ± 6

 

KMG

23 ± 8#

20 ± 9•

19 ± 10*#•

18 ± 7*#•

15 ± 7*#•

14 ± 9*#•

12 ± 6*#•

 

LKMG

22 ± 10#

16 ± 8*#•

20 ± 9#•

19 ± 8*#•

19 ± 12

18 ± 12

18 ± 9

SpO2 (%)

CG

99.0 ± 1.6

99.1 ± 1.7

99.7 ± 0.4

99.2 ± 0.7

99.5 ± 0.5

99.6 ± 0.5

99.6 ± 0.5

 

MG

96.7 ± 1.6

98.2 ± 1.8

98.6 ± 1.3

98.2 ± 1.2

98.2 ± 1.3

98.2 ± 2.0

98.5 ± 2.0

 

LG

99 ± 1.3

99 ± 1.0

97.8 ± 2.2

97.5 ± 2.6

98.6 ± 1.1

98.6 ± 1.5

99 ± 0.7

 

KG

99.5 ± 0.5

99.2 ± 1.1

99.2 ± 0.4

98.8 ± 0.9

99.3 ± 0.5

98.7 ± 1.0

99.1 ± 0.8

 

LMG

99.3 ± 0.7

99.2 ± 1.1

98.7 ± 1.7

98.2 ± 2.1

98.7 ± 1.9

99.2 ± 0.7

99.3 ± 1.0

 

KMG

99.2 ± 1.0

99.1 ± 0.8

98.3 ± 1.6

99.1 ± 0.8

98.7 ± 0.8

98.8 ± 0.9

99 ± 0.5

 

LKMG

99.5 ± 0.5

99.6 ± 0.5

99.2 ± 0.8

99.5 ± 0.7

99.2 ± 0.8

99.6 ± 0.7

99.6 ± 0.7

Etiso (V%)

CG

1.4 ± 0.2

1.4 ± 0.1

1.4 ± 0.2

1.4 ± 0.1

1.4 ± 0.4

1.2 ± 0.2

0.7 ± 0.2

 

MG

0.8 ± 0.1

1.3 ± 0.4

1.4 ± 0.6

1.6 ± 0.2

1.7 ± 0.2

1.6 ± 0.2

0.9 ± 0.4

 

LG

1.4 ± 0.2

1.4 ± 0.3

1.3 ± 0.1

1.3 ± 0.2

1.2 ± 0.1

1.1 ± 0.1

1.0 ± 0.2

 

KG

1.2 ± 0.1

1.2 ± 1.1

1.3 ± 0.1

1.3 ± 0.1

1.3 ± 0.2

1.2 ± 0.2

1.0 ± 0.2

 

LMG

1.4 ± 0.1

1.3 ± 0.1

1.3 ± 0.07

1.4 ± 0.1

1.3 ± 0.08

1.3 ± 0.1

1.3 ± 0.1

 

KMG

1.4 ± 0.2

1.4 ± 0.1

1.2 ± 0.1

1.3 ± 0.1

1.3 ± 0.1

1.3 ± 1.09

1.2 ± 0.1

 

LKMG

1.4 ± 0.2

1.2 ± 0.1

1.2 ± 0.1

1.2 ± 0.1

1.2 ± 0.2

1.1 ± 0.1

0.9 ± 0.2

ETCO2

CG

33.1 ± 8.6

34.6 ± 8.9

34.6 ± 6.6

35 ± 6.6

35.8 ± 6.8

35.3 ± 6.8

34.6 ± 7.1

 

MG

33.9 ± 3.8

37.4 ± 5.7

38.4 ± 6.2

38.4 ± 5.6

38.5 ± 5.4

39.8 ± 5.8

40.3 ± 5.7

 

LG

26 ± 7.7

28.8 ± 7.7

27.8 ± 8.7

26.9 ± 9.7

27.1 ± 10

29.5 ± 10.3

29.1 ± 11.7

 

KG

34.5 ± 6.2

35.6 ± 8.6

33.6 ± 9.9

30.6 ± 9.7

31.8 ± 7.9

32.8 ± 7.9

31.3 ± 8.2

 

LMG

27.5 ± 4.7

30.5 ± 8.8

31 ± 9.3

29.7 ± 8.9

30.5 ± 8.6

30.9 ± 9.1

30.6 ± 9.8

 

KMG

27.7 ± 10.2

29.5 ± 8.3

32.8 ± 9.9

34.6 ± 11.6

34.1 ± 9.5

34.4 ± 9.2

34.2 ± 9.8

 

LKMG

32.5 ± 9.3

34.2 ± 8.9

37 ± 10.1

37.8 ± 10.2

36.3 ± 9.3

36.4 ± 10.4

36.3 ± 8.8

T (°C)

CG

37.6 ± 0.8

37.6 ± 0.5

36.9 ± 0.6

36.6 ± 0.8

36.5 ± 0.8

37.0 ± 0.6

37.0 ± 0.7

 

MG

37.8 ± 0.9

38.0 ± 0.6

37.9 ± 0.5

37.8 ± 0.5

37.7 ± 0.5

37.7 ± 0.5

37.7 ± 0.6

 

LG

37.3 ± 0.4

37.1 ± 0.4

36.9 ± 0.4

36.7 ± 0.4

36.4 ± 0.5

36.2 ± 0.4

36.7 ± 0.5

 

KG

37.7 ± 0.4

37.4 ± 0.4

37.2 ± 0.4

36.8 ± 0.4

36.3 ± 0.6

36.3 ± 0.4

36.0 ± 0.3

 

LMG

37.0 ± 0.8

36.8 ± 0.7

36.6 ± 0.7

36.4 ± 0.8

36.2 ± 0.8

36.1 ± 0.9

35.8 ± 0.9

 

KMG

37.2 ± 0.5

37.0 ± 0.5

36.9 ± 0.6

36.5 ± 0.6

36.5 ± 0.6

36.4 ± 0.4

35.9 ± 0.4

 

LKMG

37.7 ± 0.5

37.4 ± 0.4

37.2 ± 0.4

36.9 ± 0.4

36.6 ± 0.5

36.2 ± 0.4

35.8 ± 0.5

  1. CG control group; MG maropitant group; LG lidocaine group; LMG lidocaine and maropitant group; KG ketamine group; KMG ketamine and maropitant group; LKMG lidocaine, ketamine, and maropitant group. T esophageal temperature; RR respiratory rate; HR heart rate; SpO2 oxygen saturation; Etiso expired isoflurane concentration; EtCO2 partial pressure of carbon dioxide at the end of expiration; SBP systolic blood pressure
  2. *Significant difference relative to CG
  3. #Significant difference between MG and treatment groups
  4. •Significant difference between LG and treatment groups. bmp beats per minute; mpm, movement per minute. M1, preoperatively; M2, after incision of the linea alba; M3, after right pedicle clamping; M4, after left pedicle clamping; M5, after ligation of the uterus body; M6, suture of the abdominal muscles; and M7, at the end of the surgery
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Acta Veterinaria Scandinavica

ISSN: 1751-0147