Table 1 Associations between mast cell density and clinicopathological parameters in canine mammary carcinomas

 Histological type (n = 134)

 Carcinoma simple (n = 24)

225 (132)

NS

180 (181)

NS

60 (64)

NS

 Carcinoma solid (n = 19)

168 (160)

144 (124)

50 (66)

 Comedocarcinoma (n = 9)

138 (234)

120 (165)

18 (71)

 Carcinoma arising in a complex/mixed tumour (n = 3)

122¹

98¹

29¹

 Carcinoma complex (n = 30)

138 (108)

113 (100)

31.5 (43)

 Carcinoma mixed (n = 32)

152 (187)

127 (165)

18.5 (60)

 Intraductal papillary carcinoma (n = 13)

106 (189)

100 (105)

22 (47)

 Adenosquamous carcinoma (n = 4)

195 (108)

147 (85)

48 (58)

 Histological grade (n = 134)

 Grade I (n = 73)

150 (153)

NS

114 (122)^a

0.041

29 (62)

NS

 Grade II (n = 34)

173 (194)

164 (170)^a

50 (53)

 Grade III (n = 27)

168 (170)

140 (116)

48 (75)

 Tumour necrosis (n = 134)

 Absent (n = 73)

164 (161)

NS

136 (119)

NS

35 (65)

NS

 Present (n = 61)

168 (167)

136 (119)

48 (59)

 Tumour-infiltrating

 lymphocytes (n = 112)

 lymphocytes (n = 114)

 Low (n = 55)

140 (142)

NS

100 (114)

NS

30 (49)^a

0.41

 Moderate (n = 38)

172 (142)

137 (128)

28.5 (42)

 High (n = 19)

194 (118)

153 (106)

64 (74)^a

 Proliferation index (n = 134)

 ≤ 11% (n = 66)

144 (156)

NS

118.5 (138)

NS

26 (63)

NS

 > 11% (n = 67)

170 (134)

142 (84)

50 (61)

 Tumour size (n = 45)

 T1 < 3 cm (n = 11)

90 (153)

NS

76 (155)

NS

18 (46)

0.02

 T2 3–5 cm (n = 10)

152 (156)

127.5 (142)

15 (40)^a

 T3 > 5 cm (n = 24)

174 (158)

118 (120)

50 (66)^a

 Lymph node metastasis (n = 45)

 No (n = 35)

111 (155)

NS

97.5 (144)

NS

14 (19)

0.024

 Yes (n = 10)

166 (127)

118 (118)

48 (55)