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Table 2 Mean percentage (%) and standard deviation (SD) of CD4 + and CD8 + cells and their ratio before and after antileishmanial treatment at resting phase and following LSA or PMA/iono immunostimulation

From: Intracellular IFN-γ and IL-4 levels of CD4 + and CD8 + T cells in the peripheral blood of naturally infected (Leishmania infantum) symptomatic dogs before and following a 4-week treatment with miltefosine and allopurinol: a double-blinded, controlled and cross-sectional study

 

CD4 + cells

CD8 + cells

CD4 + /CD8 + ratio

Before treatment

After treatment

Controls

Before treatment

After treatment

Controls

Before treatment

After treatment

Controls

Resting phase

30.28 (1.42)

35.83 (1.61)

41.74 (5.88)

26.64 (2.13)

18.59 (1.38)

16.39 (2.90)

1.14 (0.13)

1.91 (0.07)

2.58 (0.42)

PMA/iono immunostimulation

23.79 (8.49)

30.59 (1.15)

35.94 (5.50)

18.09 (0.72)

15.46 (0.55)

11.99 (2.13)

1.46 (0.06)

1.97 (0.06)

3.03 (0.39)

LSA immunostimulation

29.83 (0.60)

35.49 (1.66)

38.37 (5.51)

26.50 (1.40)

19.08 (0.88)

16.43 (3.13)

1.12 (0.04)

1.86 (0.13)

2.4 (0.52)