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Table 2 Cardiorespiratory data from castrations performed in animal hospital

From: Dissociative Anaesthesia During Field and Hospital Conditions for Castration of Colts

Variables

Protocol

ANE 5'

ANE 15'

ANE 25'

ANE 35'

Post

Within protocol

Between protocols

HR

RZ

34 (4)

36 (3)

34 (2)

32 (0)

34 (6)

NS

NS

Beats/min

ARZ

35 (4)

35 (4)

35 (4)

36 (7)

37 (3)

NS

 
 

ARBZ

33 (5)

32 (4)

33 (6)

34 (7)

33 (7)

NS

 

SAP mean

RZ

157 (27)*

142 (26)

131 (30)

118 (16)

107 (10)

0.03

RZ-ARZ 0.023

RZ-ARBZ 0.048

mm Hg

ARZ

136 (11) #

123 (16)* #

106 (17) #

100 (11) #

104 (6)

<0.01

 
 

ARBZ

128 (20) #

126 (16) #

124 (22) #

110 (19) #

115 (22)

NS

 

RR

RZ

24 (15)

32 (13)

24 (10)

22 (4)

17 (8)

NS

NS

Breaths/min

ARZ

24 (10)

33 (12)

26 (8)

27 (9)

[12 (4)]

NS

 
 

ARBZ

17 (6)

19 (7)

20 (7)

19 (5)

14 (3)

NS

 

PaCO2

RZ

5.9 (0.3)

5.6 (0.5)*

5.6 (0.4)*

[5.7 (0.2)]

6.1 (0.3)

<0.01

NS

kPa

ARZ

6.2 (0.4)

6.1 (0.6)

6.0 (0.5)

6.2 (0.4)

6.0 (0.4)

NS

 
 

ARBZ

6.4 (0.5)

6.1 (0.5)

6.4 (0.3)

6.3 (0.3)

6.2 (0.4)

NS

 

PaO2

RZ

7.7 (1.0)*

7.4 (1.0)*

7.4 (1.5)*

[6.9 (0.3)]

12.5 (0.8)

<0.01

NS

kPa

ARZ

8.0 (1.0)*

8.0 (1.2)*

8.1 (1.4)*

8.6 (1.5)*

12.9 (1.3)

<0.01

 
 

ARBZ

8.3 (1.6)*

8.4 (1.9)*

7.5 (1.8)*

8.4 (2.0)*

13.5 (1.4)

<0.01

 

PjvO2

RZ

4.2 (0.4)

4.2 (0.3)

4.2 (0.4)

[4.6 (0.4)]

4.4 (0.6)

NS

RZ-ARBZ 0.003

kPa

ARZ

4.4 (0.4)

4.5 (0.4)

4.7 (0.5)

4.7 (0.5)

4.7 (0.6)

NS

 
 

ARBZ

5.0 (0.5) #

4.9 (0.4) #

4.8 (0.6) #

5.0 (0.4)

5.3 (0.5) #

NS

 

C(a-jv)O2

RZ

5.0 (1.0)

4.5 (1.5)

4.1 (2.2)

[2.8 (0.5)]

5.0 (1.6)

NS

NS

ml/100 ml

ARZ

4.4 (1.1)

3.8 (1.0)

3.4 (1.0)

3.3 (1.0)

4.0 (1.2)

NS

 
 

ARBZ

3.8 (0.8)

3.7 (0.7)

3.2 (0.5)

2.9 (0.8)

3.8 (1.1)

NS

 
  1. Data presented as mean (SD) for heart rate (HR), mean systemic arterial pressure (SAP mean), respiratory rate (RR), arterial carbon dioxide tension (PaCO2), arterial oxygen tension (PaO2), jugular venous oxygen tension (PjvO2) and arterial – jugular venous oxygen tension difference (C(a-jv)O2). Protocol = anaesthetic protocol: romifidine and tiletamine/zolazepam (RZ); acepromazine, romifidine and tiletamine/zolazepam (ARZ); acepromazine, romifidine, butorphanol and tiletamine/zolazepam (ARBZ). ANE 5', 15', 25' and 35' = measurements at 5, 15, 25 and 35 minutes of anaesthesia. Post = 5 minutes after the horse had regained the standing position. Within protocol = p value for 1-way ANOVA run for each protocol from ANE 5' to Post. * = Significant different compared to Post. Between protocol = p value for 2-way ANOVA during anaesthesia. # =significantly different from RZ. Values within brackets [] not included in statistical analysis (n = 3-5). NS = not significant.