Table 4 Gluteal muscle content of metabolites in healthy and colic horses. The muscle content of adenosine triphosphate (ATP), adenosine diphosphate (ADP), adenosine monophosphate (AMP), inosine monophosphate (IMP), creatine phosphate (CP), creatine (Cr) and lactate (La) from after induction of anaesthesia to one day after anaesthesia in healthy (plain style) and colic horses (bold) with the American Society of Anaesthesiologists physical status 5 (ASA 5) colic horses shown separately (italic). The figures within parenthesis are the number (n) of horses included at each measurement.
From: Metabolism before, during and after anaesthesia in colic and healthy horses
| Â | ANAESTHESIA START | ANAESTHESIA END | POST 1 | DAY 1 | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
mmol/kg d.w. | ||||||||||||
| Â | Median | Range | (n) | Median | Range | (n) | Median | Range | (n) | Median | Range | (n) |
ATP | 26.0 | 22.2–28.4 | (20) | 26.1 | 21.7–29.4 | (20) | 25.0c | 17.3–27.3 | (7) | 22.4c | 19.8–27.5 | (6) |
|  | 23.0* | 17.9–32.6 | (15) | 22.0* | 17.5–29.9 | (14) | 23.8 | 21.2–25.6 | (7) | 22.7 | 18.8–30.1 | (13) |
|  | 24.4 | 16.4–25.1 | (3) |  | 13.9–24.3 | (2) |  |  |  |  |  |  |
ADP | 4.0 | 3.4–4.1 | (7) | 4.3 | 3.7–4.4 | (7) | 4.0 | 3.2–4.2 | (7) | 4.0 | 3.7–5.0 | (6) |
|  | 4.3 | 3.7–5.2 | (15) | 4.5 | 3.6–5.3 | (14) | 4.5 | 4.0–5.2 | (7) | 4.3 | 3.9–5.2 | (13) |
|  | 4.3 | 3.5–4.5 | (3) |  | 3.3–5.2 | (2) |  |  |  |  |  |  |
AMP | 0.16 | 0.06–0.31 | (20) | 0.18 | 0.06–0.37 | (20) | 0.26 | 0.14–0.32 | (7) | 0.34 | 0.23–0.49 | (6) |
|  | 0.28* | 0.20–0.35 | (15) | 0.28* | 0.18–0.38 | (14) | 0.31 | 0.21–0.39 | (7) | 0.26 | 0.20–0.45 | (13) |
|  | 0.24 | 0.16–0.25 | (3) |  | 0.23–0.35 | (2) |  |  |  |  |  |  |
IMP | 0.11 | 0.00–0.57 | (20) | 0.06 | 0.00–0.43 | (20) | 0.17bc | 0.00–0.35 | (7) | 0.24bc | 0.07–1.04 | (6) |
|  | 0.03* | 0.00–0.18 | (15) | 0.08 B | 0.00–0.41 | (14) | 0.07 | 0.03–0.12 | (7) | 0.05 | 0.00–0.15 | (13) |
|  | 0.04 | 0.00–0.23 | (3) |  | 0.07–1.02 | (2) |  |  |  |  |  |  |
CP | 60.4 | 41.5–89.2 | (20) | 65.2 | 32.3–83.0 | (20) | 58.9 | 50.6–75.3 | (7) | 54.6 | 43.4–68.0 | (6) |
|  | 56.1 | 26.7–77.0 | (15) | 44.1 | 19.7–77.8 | (14) | 53.0 | 31.3–73.5 | (7) | 65.8 E | 34.2–81.1 | (13) |
|  | 70.7 | 22.8–74.6 | (3) |  | 60.3–62.5 | (2) |  |  |  |  |  |  |
Cr | 55.8 | 52.2–67.1 | (7) | 59.8 | 56.5–74.4 | (7) | 53.0bc | 44.0–56.0 | (7) | 47.4 | 39.1–80.5 | (6) |
|  | 74.6* | 50.2–106.3 | (14) | 82.1* | 49.5–111.9 | (13) | 83.5* | 60.7–114.0 | (7) | 66.4* E | 43.1–110.4 | (13) |
|  | 63.5 | 54.2–109.0 | (3) |  | 68.2–129.9 |  |  |  |  |  |  |  |
La | 13.8 | 5.9–29.5 | (18) | 20.0b | 10.9–46.2 | (19) | 22.1b | 6.1–34.0 | (6) | 16.5ce | 10.4–39.1 | (6) |
|  | 22.5* | 14.9–36.2 | (15) | 31.3* B | 20.0–54.9 | (14) | 17.6 | 11.7–58.9 | (7) | 17.1 C | 8.9–37.5 | (12) |
|  | 38.1 | 37.9–57.5 | (3) |  | 83.0–100.2 | (2) |  |  |  |  |  |  |