In vivo and in vitro evaluation of an Acetobacter xylinum synthesized microbial cellulose membrane intended for guided tissue repair

Table 1 Scores¹attributed to the level of infiltration with polymorphonuclear cells (PMNs), multinucleated giant cells (MGCs), and lymphocytes, and development of angiogenesis and fibrosis at seven, 15, 30, 60 and 90 days post-operatively.

	Time points of evaluation (days)
Cells/event	7	15	30	60	90
PMNs	0.5² (0/1)^3,a	0.5 (0/2)^a	0 (0/0)^a	0 (0/0)^a	0 (0/0)^a
MGCs	0 (0/0)^a	0 (0/0)^a	0 (0/0)^a	0 (0/0)^a	0 (0/0)^a
Lymphocytes	1 (0/2)^a	0 (0/0)^a	0.2 (0/1)^a	0 (0/0)^a	0 (0/0)^a
Angiogenesis	2 (1/3)^a	2 (1/3)^ab	1 (1/2)^ab	1 (1/1)^ab	1 (0/1)^b
Fibrosis	1.5 (1/3)^a	1.5 (1/3)^a	1 (1/1)^ab	1 (0/1)^ab	0 (0/1)^b

¹ Scores: absent (0), mild (1), intense (2), and severe (3);
²Mean score of analysis;
³The number inside parenthesis represents the minimal and the maximal score observed in the event;
Values followed by different letters (a or b) on horizontal were significantly different (P < 0.05)

ISSN: 1751-0147