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Table 7 Ī”Cq1-values (mean Ā± SD) of hepatic mRNA expression of the genes PPARĪ±2, PPARĪ³3, SREBP14, TNFĪ±5in CLA supplemented cows vs. control group before (week -1), during (week 2 and 4) and after (week 8) treatment6.

From: Rumen-protected conjugated linoleic acid supplementation to dairy cows in late pregnancy and early lactation: effects on milk composition, milk yield, blood metabolites and gene expression in liver

Ā 

Control (n = 5)

CLA (n = 5)

Ā 

week -1

week 2

week 4

week 8

week -1

week 2

week 4

week 8

Ā 

mean

SD

mean

SD

mean

SD

mean

SD

mean

SD

mean

SD

mean

SD

mean

SD

Ī”PPARĪ±

1.5

0.3

1.4

0.2

1.9

0.3

1.7

0.5

2.0

0.1

1.4

0.3

1.9

0.7

2.0

0.5

Ī”PPARĪ³

7.8

0.8

9.6

2.3

9.8

2.4

9.4

0.8

9.1

0.3

8.6

0.2

9.2

0.7

9.2

0.2

Ī”SREBP1

2.3

1.6

4.0

2.9

4.0

1.8

4.2

1.6

3.0

0.2

3.7

0.7

4.1

1.2

3.1

0.5

Ī”TNFĪ±

9.3

0.6

8.9

0.4

9.4

0.7

9.4

1.2

8.5

0.4

8.0

1.1

8.5

1.5

8.4

0.4

  1. 1 Ī”Cq-values were calculated as Ī”Cq = Cqtarget gene - meanCqrefence genes
  2. 2 peroxisome proliferator-activated receptor-alpha.
  3. 3peroxisome proliferator-activated receptor-gamma.
  4. 4sterol regulatory element-binding protein-1.
  5. 5tumor necrosis factor-alpha.
  6. 6CLA supplemented timeframe: day 1 till day 28 of lactation; five primiparous cows received a special supplement including rumen-protected CLA (10 g c 9,t 11-CLA/day and t 10,c 12-CLA/day).