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Table 2 Data obtained from calves (n = 8) experimentally inoculated with A663 and N569 strains of bovine herpesvirus (BoHV) 5.

From: Comparative study on the in vitro and in vivo properties of two bovine herpesvirus-5 reference strains

Group Animal no. Viral excretion* (peak titre) Severity of histopathological changes (mean)** DNA in TG SN Abs titre(log)*** Nasal IgA
BoHV-5 N569 636 2-12 (6) +++ + 1.5 +
  628 7-15 (5) ++ + 1.05 -
  199 Intermittent (4.3) - - 1.5 +
  191 - - - - -
BoHV-5 A663 192 2-12 (6.5) +++ + 0.9**** -
  619 2-6 (5.5) +++ + 0.9 +
  185 Intermittent (2.3) + + 0.9 +
  254 2-12 (6.3) + + 0.9 +
  1. *Viral excretion is expressed as log TCID50/ml. **Score based on the presence of the following CNS histopathological alterations: vascular alteration, inflammation, focal gliosis, infiltration by macrophages and malacia. References: +++: severe; ++: moderate; +: slight; -:negative. ***Serum neutralizing (SN) antibodies (Abs) at day 34 post infection (pi). ****Animal 192 was euthanized 15 days pi, the titre of SN Abs corresponds to this date.