Figure 5

Histology of the tumour in the cervical vertebral column. (A) Section of tumour showing chordoid tumour cells in lacunaes (arrows) surrounded by connective tissue. The tumour infiltrated and replaced pre-existing, normally differentiated trabecular bone tissue (b). Multifocally there was chondroid differentiation in the tumour (c) (H&E, Bar 200 μm). (B) Physaliferous tumour cells, which are characteristic of chordomas, were observed multifocally (H&E, Bar 50 μm). (C) Section showing the tumour (t) to be locally invasive, here invading the spinal cord tissue (s) (H&E, Bar 200 μm).