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Table 2 The clinical diagnosis for group 1a (IMHA), group 1b (anaemia, no IMHA), group 2 (microcytosis), group 3 (hyperlipidemia), group 4 (lymphoma), and group 5 (infections)

From: The use of the rapid osmotic fragility test as an additional test to diagnose canine immune-mediated haemolytic anaemia

Group

Disease category

Diseases

1a (n = 19)

Immune-mediated haemolytic anaemia

Primary immune-mediated haemolytic anaemia (n = 17), secondary immune-mediated haemolytic anaemia (n = 2): right hind limb abscess, after Permethrin and Imidacloprida treatment

1b (n = 21)

Anaemia, no immune-mediated haemolytic anaemia

Splenic hemangiosarcoma (n = 5), histiocytic sarcoma (n = 2), disseminated mastocytoma (n = 1), gastro-intestinal bleeding due to long-term NSAID administration (n = 2) and intestinal neoplasia (n = 2), coumarine intoxication (n = 2), methemoglobinemia due to onion intoxication (n = 1), blood loss due to immune-mediated thrombocytopenia (n = 2), chronic kidney disease (n = 1), hypoadrenocorticism (n = 1), factor X deficiency (n = 1), anaemia of inflammatory disease (n = 1)

2 (n = 8)

Microcytosis

Iron deficiency due to chronic gastro-intestinal blood loss (n = 6), hypoadrenocorticism (n = 1), portosystemic shunt (n = 1)

3 (n = 13)

Hyperlipidemia

Hyperadrenocorticism (n = 7), diabetic ketoacidosis with pancreatitis (n = 1), pancreatitis (n = 1), cholestatic liver disease (n = 1), hypothyroidism (n = 1), nephrotic syndrome (n = 1), primary hyperlipidemia (n = 1)

4 (n = 10)

Multicentric Lymphoma

B-cell lymphoma (n = 5), T-cell lymphoma (n = 2), lymphoma with unknown immunophenotype (n = 3)

5 (n = 8)

Infectious disease

Pyometra (n = 2), septic peritonitis (n = 2), prostatitis (n = 1), chronic Erlichiosis (n = 1), Leishmaniasis (n = 1), septic pericarditis (n = 1)

  1. aAdvantix®, Bayer Health Care, Brussels, Belgium.