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Table 3 Results of the packed cell volume, mean corpuscular volume, cholesterol and triglyceride concentration, number of spherocytes, in-saline auto-agglutination and Coombs’ test for group 1a (IMHA), group 1b (anaemia, no IMHA), group 2 (microcytosis), group 3 (hyperlipidemia), group 4 (lymphoma), group 5 (infections) and group 6 (healthy)

From: The use of the rapid osmotic fragility test as an additional test to diagnose canine immune-mediated haemolytic anaemia

 

Group 1a (n = 19)

Group 1b (n = 21)

Group 2 (n = 8)

Group 3 (n = 13)

Group 4 (n = 10)

Group 5 (n = 8)

Group 6 (n = 13)

Packed Cell Volume (%)

13.6 ± 4.8

17.9 ± 4.3

25.0 ± 14.7

46.8 ± 9.9

44.1 ± 11.8

30.3 ± 15.1

46.9 ± 3.6

(7.6-23)

(7.0-25.5)

(11.0-55.2)

(18.2-57.7)

(20.5-59.4)

(14.9-61.4)

(41.7-53.2)

Mean Corpuscular Volume (fl)

76.7 ± 5.1

77.7 ± 9.3

57.1 ± 3.3

68.9 ± 8.1

70.4 ± 4.5

66.5 ± 5.4

68.7 ± 2.4

(70.7-88.4)

(67.1-96.3)

(50.4-60.0)

(62.7-77.2)

(62.9-77.3)

(60.0-76.7)

(63.0-71.2)

Cholesterol concentration (mmol/l)

6.73 ± 1.37

4.68 ± 3.18

3.58 ± 1.83

16.6 ± 11.0

4.95 ± 1.44

6.33 ± 1.48

6.81 ± 1.45

(5.3-8.53)*

(0.83-12.7)**

(2.48-8.35)

(6.26-48.38)

(2.77-7.11)

(4.0-9.0)

(4.42-9.15)

Triglyceride Concentration (mmol/l)

0.87 ± 0.30

0.76 ± 0.28

0.71 ± 0.44

11.73 ± 9.36

0.75 ± 0.31

0.90 ± 0.34

0.89 ± 0.56

(0.57-1.25)*

(0.41-1.19)**

(0.24-1.72)

(0.86-29.26)

(0.44-1.34)

(0.52-1.56)

(0.31-1.99)

Number of spherocytes per high power field

<1

3

13

7

11

10

7

13

1-3

2

4

1

2

0

0

0

3-5

2

3

0

0

0

0

0

≥5

12

1

0

0

0

1

0

In-saline auto-agglutination

Positive

16

0

0

0

0

0

0

Negative

3

21

8

13

10

8

13

Coombs’ test

Positive

13

1

0

0

0

2

0

Negative

4***

20

8

13

10

6

13

  1. The data of the packed cell volume, the mean corpuscular volume, the cholesterol and triglyceride concentration are expressed as mean ± standard deviation (range).
  2. *Total serum cholesterol and triglyceride concentrations were measured in 4/19 group 1a dogs.
  3. **Total serum cholesterol and triglyceride concentrations were measured in 13/21 group 1b dogs.
  4. ***Coombs’ test was performed in 17/19 group 1a dogs.