Figure 4From: SagE induces highly effective protective immunity against Streptococcus iniae mainly through an immunogenic domain in the extracellular regionSerum antibody production in vaccinated fish. Sera were taken from flounder vaccinated with pSagE, pSagECR, and PBS (control). Serum antibodies against ECR were determined by ELISA. Values are shown as means ± SE (N = 5). *P < 0.05; **P < 0.01.Back to article page